Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health
Phytonutrients are natural bioactive components present in the daily diet that can exert a positive impact on human health. Studies have shown that phytonutrients may act as antioxidants and improve metabolism after being ingested, which help to regulate physiological processes and prevent metabolic...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.960309/full |
| _version_ | 1798039969550303232 |
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| author | Juntao Kan Feng Wu Feijie Wang Jianheng Zheng Junrui Cheng Yuan Li Yuexin Yang Jun Du |
| author_facet | Juntao Kan Feng Wu Feijie Wang Jianheng Zheng Junrui Cheng Yuan Li Yuexin Yang Jun Du |
| author_sort | Juntao Kan |
| collection | DOAJ |
| description | Phytonutrients are natural bioactive components present in the daily diet that can exert a positive impact on human health. Studies have shown that phytonutrients may act as antioxidants and improve metabolism after being ingested, which help to regulate physiological processes and prevent metabolic disorders and diseases. However, their efficacy is limited by their low bioavailability. The gut microbiota is symbiotic with humans and its abundance and profile are related to most diseases. Interestingly, studies have shown that the gut microbiota is associated with the metabolism of phytonutrients by converting them into small molecules that can be absorbed by the body, thereby enhancing their bioavailability. Furthermore, phytonutrients can modulate the composition of the gut microbiota, and therefore improve the host's health. Here, we focus on uncovering the mechanisms by which phytonutrients and gut microbiota play roles in health, and the interrelationships between phytonutrients and gut microbiota were summarized. We also reviewed the studies that reported the efficacy of phytonutrients in human health and the future directions. |
| first_indexed | 2024-04-11T22:01:02Z |
| format | Article |
| id | doaj.art-12dfbdadd1414a7cac7e54f368ffdec9 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-11T22:01:02Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-12dfbdadd1414a7cac7e54f368ffdec92022-12-22T04:00:55ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-08-01910.3389/fnut.2022.960309960309Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human healthJuntao Kan0Feng Wu1Feijie Wang2Jianheng Zheng3Junrui Cheng4Yuan Li5Yuexin Yang6Jun Du7Nutrilite Health Institute, Shanghai, ChinaSequanta Technologies Co., Ltd., Shanghai, ChinaNutrilite Health Institute, Shanghai, ChinaNutrilite Health Institute, Shanghai, ChinaDepartment of Molecular and Structural Biochemistry, North Carolina State University, Kannapolis, NC, United StatesSequanta Technologies Co., Ltd., Shanghai, ChinaChinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Beijing, ChinaNutrilite Health Institute, Shanghai, ChinaPhytonutrients are natural bioactive components present in the daily diet that can exert a positive impact on human health. Studies have shown that phytonutrients may act as antioxidants and improve metabolism after being ingested, which help to regulate physiological processes and prevent metabolic disorders and diseases. However, their efficacy is limited by their low bioavailability. The gut microbiota is symbiotic with humans and its abundance and profile are related to most diseases. Interestingly, studies have shown that the gut microbiota is associated with the metabolism of phytonutrients by converting them into small molecules that can be absorbed by the body, thereby enhancing their bioavailability. Furthermore, phytonutrients can modulate the composition of the gut microbiota, and therefore improve the host's health. Here, we focus on uncovering the mechanisms by which phytonutrients and gut microbiota play roles in health, and the interrelationships between phytonutrients and gut microbiota were summarized. We also reviewed the studies that reported the efficacy of phytonutrients in human health and the future directions.https://www.frontiersin.org/articles/10.3389/fnut.2022.960309/fullphytonutrientsgut microbiotametabolismhealth outcomesbioavailability |
| spellingShingle | Juntao Kan Feng Wu Feijie Wang Jianheng Zheng Junrui Cheng Yuan Li Yuexin Yang Jun Du Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health Frontiers in Nutrition phytonutrients gut microbiota metabolism health outcomes bioavailability |
| title | Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health |
| title_full | Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health |
| title_fullStr | Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health |
| title_full_unstemmed | Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health |
| title_short | Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health |
| title_sort | phytonutrients sources bioavailability interaction with gut microbiota and their impacts on human health |
| topic | phytonutrients gut microbiota metabolism health outcomes bioavailability |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.960309/full |
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