A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection.

A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection.

The innate immune response provides the first line of defense against viruses and other pathogens by responding to specific microbial molecules. Influenza A virus (IAV) produces double-stranded RNA as an intermediate during the replication life cycle, which activates the intracellular pathogen recog...

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Bibliographic Details
Main Authors: Jonathan Maelfait, Kenny Roose, Pieter Bogaert, Mozes Sze, Xavier Saelens, Manolis Pasparakis, Isabelle Carpentier, Geert van Loo, Rudi Beyaert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3291650?pdf=render

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