Radiomics and radiogenomics of primary liver cancers
Concurrent advancements in imaging and genomic biomarkers have created opportunities to identify non-invasive imaging surrogates of molecular phenotypes. In order to develop such imaging surrogates radiomics and radiogenomics/imaging genomics will be necessary; there has been consistent progress in...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Association for the Study of the Liver
2019-03-01
|
| Series: | Clinical and Molecular Hepatology |
| Subjects: | |
| Online Access: | http://e-cmh.org/upload/pdf/cmh-2018-1007.pdf |
| _version_ | 1811199302534430720 |
|---|---|
| author | Woo Kyoung Jeong Neema Jamshidi Ely Richard Felker Steven Satish Raman David Shinkuo Lu |
| author_facet | Woo Kyoung Jeong Neema Jamshidi Ely Richard Felker Steven Satish Raman David Shinkuo Lu |
| author_sort | Woo Kyoung Jeong |
| collection | DOAJ |
| description | Concurrent advancements in imaging and genomic biomarkers have created opportunities to identify non-invasive imaging surrogates of molecular phenotypes. In order to develop such imaging surrogates radiomics and radiogenomics/imaging genomics will be necessary; there has been consistent progress in these fields for primary liver cancers. In this article we evaluate the current status of the field specifically with regards to hepatocellular carcinoma and intrahepatic cholangiocarcinoma, highlighting some of the up and coming results that were presented at the annual Radiological Society of North America Conference in 2017. There are an increasing number of studies in this area with a bias towards quantitative feature measurement, which is expected to benefit reproducibility of the findings and portends well for the future development of biomarkers for diagnosis, prognosis, and treatment response assessment. We review some of the advancements and look forward to some of the exciting future applications that are anticipated as the field develops. |
| first_indexed | 2024-04-12T01:45:42Z |
| format | Article |
| id | doaj.art-12e68c6670dc4230b1c5082a994ebd58 |
| institution | Directory Open Access Journal |
| issn | 2287-2728 2287-285X |
| language | English |
| last_indexed | 2024-04-12T01:45:42Z |
| publishDate | 2019-03-01 |
| publisher | Korean Association for the Study of the Liver |
| record_format | Article |
| series | Clinical and Molecular Hepatology |
| spelling | doaj.art-12e68c6670dc4230b1c5082a994ebd582022-12-22T03:53:05ZengKorean Association for the Study of the LiverClinical and Molecular Hepatology2287-27282287-285X2019-03-01251212910.3350/cmh.2018.10071434Radiomics and radiogenomics of primary liver cancersWoo Kyoung Jeong0Neema Jamshidi1Ely Richard Felker2Steven Satish Raman3David Shinkuo Lu4 Department of Radiological Science, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA Department of Radiological Science, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA Department of Radiological Science, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA Department of Radiological Science, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA Department of Radiological Science, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USAConcurrent advancements in imaging and genomic biomarkers have created opportunities to identify non-invasive imaging surrogates of molecular phenotypes. In order to develop such imaging surrogates radiomics and radiogenomics/imaging genomics will be necessary; there has been consistent progress in these fields for primary liver cancers. In this article we evaluate the current status of the field specifically with regards to hepatocellular carcinoma and intrahepatic cholangiocarcinoma, highlighting some of the up and coming results that were presented at the annual Radiological Society of North America Conference in 2017. There are an increasing number of studies in this area with a bias towards quantitative feature measurement, which is expected to benefit reproducibility of the findings and portends well for the future development of biomarkers for diagnosis, prognosis, and treatment response assessment. We review some of the advancements and look forward to some of the exciting future applications that are anticipated as the field develops.http://e-cmh.org/upload/pdf/cmh-2018-1007.pdfHepatocellular carcinomaCholangiocarcinomaTumor biomarkerComputed tomographyGenomics |
| spellingShingle | Woo Kyoung Jeong Neema Jamshidi Ely Richard Felker Steven Satish Raman David Shinkuo Lu Radiomics and radiogenomics of primary liver cancers Clinical and Molecular Hepatology Hepatocellular carcinoma Cholangiocarcinoma Tumor biomarker Computed tomography Genomics |
| title | Radiomics and radiogenomics of primary liver cancers |
| title_full | Radiomics and radiogenomics of primary liver cancers |
| title_fullStr | Radiomics and radiogenomics of primary liver cancers |
| title_full_unstemmed | Radiomics and radiogenomics of primary liver cancers |
| title_short | Radiomics and radiogenomics of primary liver cancers |
| title_sort | radiomics and radiogenomics of primary liver cancers |
| topic | Hepatocellular carcinoma Cholangiocarcinoma Tumor biomarker Computed tomography Genomics |
| url | http://e-cmh.org/upload/pdf/cmh-2018-1007.pdf |
| work_keys_str_mv | AT wookyoungjeong radiomicsandradiogenomicsofprimarylivercancers AT neemajamshidi radiomicsandradiogenomicsofprimarylivercancers AT elyrichardfelker radiomicsandradiogenomicsofprimarylivercancers AT stevensatishraman radiomicsandradiogenomicsofprimarylivercancers AT davidshinkuolu radiomicsandradiogenomicsofprimarylivercancers |