Simulation of Cell Group Formation Regulated by Coordination Number, Cell Cycle and Duplication Frequency

The effects of coordination number, a cell cycle and duplication frequency on cell-group formation have been investigated in a computer simulation. In the simulation, multiplication occurs in the last three steps of a cell cycle with a probability function to give variations in the interval. Each ce...

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Bibliographic Details
Main Authors: Shigehiro Hashimoto, Motofumi Toda, Masa Mizobuchi, Takashi Kuromitsu
Format: Article
Language:English
Published: International Institute of Informatics and Cybernetics 2013-08-01
Series:Journal of Systemics, Cybernetics and Informatics
Subjects:
Online Access:http://www.iiisci.org/Journal/CV$/sci/pdfs/9S376CA.pdf
Description
Summary:The effects of coordination number, a cell cycle and duplication frequency on cell-group formation have been investigated in a computer simulation. In the simulation, multiplication occurs in the last three steps of a cell cycle with a probability function to give variations in the interval. Each cell has a constant coordination number: four or six. When a cell gets surrounded by adjacent cells, its status changes from an active stage to a resting stage. Each cell repeats multiplication, and disappears when the times of multiplication reach to the limit. Variation was made in the coordination number, in the interval of multiplication and in the limited times of multiplication. The cells of the colony, which have the larger number of coordination, have reached the larger maximum population and disappeared earlier.
ISSN:1690-4524