Simulation of Cell Group Formation Regulated by Coordination Number, Cell Cycle and Duplication Frequency

The effects of coordination number, a cell cycle and duplication frequency on cell-group formation have been investigated in a computer simulation. In the simulation, multiplication occurs in the last three steps of a cell cycle with a probability function to give variations in the interval. Each ce...

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Main Authors: Shigehiro Hashimoto, Motofumi Toda, Masa Mizobuchi, Takashi Kuromitsu
Format: Article
Language:English
Published: International Institute of Informatics and Cybernetics 2013-08-01
Series:Journal of Systemics, Cybernetics and Informatics
Subjects:
Online Access:http://www.iiisci.org/Journal/CV$/sci/pdfs/9S376CA.pdf
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author Shigehiro Hashimoto
Motofumi Toda
Masa Mizobuchi
Takashi Kuromitsu
author_facet Shigehiro Hashimoto
Motofumi Toda
Masa Mizobuchi
Takashi Kuromitsu
author_sort Shigehiro Hashimoto
collection DOAJ
description The effects of coordination number, a cell cycle and duplication frequency on cell-group formation have been investigated in a computer simulation. In the simulation, multiplication occurs in the last three steps of a cell cycle with a probability function to give variations in the interval. Each cell has a constant coordination number: four or six. When a cell gets surrounded by adjacent cells, its status changes from an active stage to a resting stage. Each cell repeats multiplication, and disappears when the times of multiplication reach to the limit. Variation was made in the coordination number, in the interval of multiplication and in the limited times of multiplication. The cells of the colony, which have the larger number of coordination, have reached the larger maximum population and disappeared earlier.
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spelling doaj.art-12e79b25714f432fb9ec45263798a1e52022-12-22T03:12:13ZengInternational Institute of Informatics and CyberneticsJournal of Systemics, Cybernetics and Informatics1690-45242013-08-011142933Simulation of Cell Group Formation Regulated by Coordination Number, Cell Cycle and Duplication FrequencyShigehiro Hashimoto0Motofumi Toda1Masa Mizobuchi2Takashi Kuromitsu3 Kogakuin University Osaka Institute of Technology Osaka Institute of Technology Osaka Institute of Technology The effects of coordination number, a cell cycle and duplication frequency on cell-group formation have been investigated in a computer simulation. In the simulation, multiplication occurs in the last three steps of a cell cycle with a probability function to give variations in the interval. Each cell has a constant coordination number: four or six. When a cell gets surrounded by adjacent cells, its status changes from an active stage to a resting stage. Each cell repeats multiplication, and disappears when the times of multiplication reach to the limit. Variation was made in the coordination number, in the interval of multiplication and in the limited times of multiplication. The cells of the colony, which have the larger number of coordination, have reached the larger maximum population and disappeared earlier.http://www.iiisci.org/Journal/CV$/sci/pdfs/9S376CA.pdf SimulationBiological CellGroup FormationCoordinationNumberDuplication FrequencyCell Cyclepopulation
spellingShingle Shigehiro Hashimoto
Motofumi Toda
Masa Mizobuchi
Takashi Kuromitsu
Simulation of Cell Group Formation Regulated by Coordination Number, Cell Cycle and Duplication Frequency
Journal of Systemics, Cybernetics and Informatics
Simulation
Biological Cell
Group Formation
Coordination
Number
Duplication Frequency
Cell Cycle
population
title Simulation of Cell Group Formation Regulated by Coordination Number, Cell Cycle and Duplication Frequency
title_full Simulation of Cell Group Formation Regulated by Coordination Number, Cell Cycle and Duplication Frequency
title_fullStr Simulation of Cell Group Formation Regulated by Coordination Number, Cell Cycle and Duplication Frequency
title_full_unstemmed Simulation of Cell Group Formation Regulated by Coordination Number, Cell Cycle and Duplication Frequency
title_short Simulation of Cell Group Formation Regulated by Coordination Number, Cell Cycle and Duplication Frequency
title_sort simulation of cell group formation regulated by coordination number cell cycle and duplication frequency
topic Simulation
Biological Cell
Group Formation
Coordination
Number
Duplication Frequency
Cell Cycle
population
url http://www.iiisci.org/Journal/CV$/sci/pdfs/9S376CA.pdf
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AT motofumitoda simulationofcellgroupformationregulatedbycoordinationnumbercellcycleandduplicationfrequency
AT masamizobuchi simulationofcellgroupformationregulatedbycoordinationnumbercellcycleandduplicationfrequency
AT takashikuromitsu simulationofcellgroupformationregulatedbycoordinationnumbercellcycleandduplicationfrequency