Identification of nanoparticle-mediated siRNA-ASPN as a key gene target in the treatment of keloids

Identification of nanoparticle-mediated siRNA-ASPN as a key gene target in the treatment of keloids

Background: Keloid, also known as connective tissue hyperplasia, is a benign proliferative disorder with a global distribution. The available therapeutic interventions are steroid injections, surgical removal of keloids, radiotherapy, compression therapy, the application of cryosurgery, and many oth...

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Bibliographic Details
Main Authors: Yipeng Dong, Chuwei Zhang, Qingrong Zhang, Zihan Li, Yixiao Wang, Jun Yan, Gujie Wu, Ling Qiu, Zhihan Zhu, Bolin Wang, Haiying Gu, Yi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
keloid
asporin gene
nanoparticle
keloid fibroblast
nude mice allograft
ASPN
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1025546/full

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