Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats
In this study, it is aimed to determine the possible effects of curcumin on hematological parameters in aflatoxin applied rats. Thirty eight healthy male Wistar Albino rats were used in the study. Group I animals was no applied. Animals in Group II were orally given 1 ml 10% DMSO daily for 60 days....
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| Format: | Article |
| Language: | English |
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Selcuk University
2020-09-01
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| Series: | Türk Spor ve Egzersiz Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/1098157 |
| _version_ | 1797500620190515200 |
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| author | Deniz Uluışık Ercan Keskin Durmuş Hatipoğlu |
| author_facet | Deniz Uluışık Ercan Keskin Durmuş Hatipoğlu |
| author_sort | Deniz Uluışık |
| collection | DOAJ |
| description | In this study, it is aimed to determine the possible effects of curcumin on hematological parameters in aflatoxin applied rats. Thirty eight healthy male Wistar Albino rats were used in the study. Group I animals was no applied. Animals in Group II were orally given 1 ml 10% DMSO daily for 60 days. Animals in Group III were orally given 300 mg/kg curcumin dissolved in 10% DMSO daily for 60 days. Animals in Group IV were orally given 250 µg/kg aflatoxin B1 dissolved in 10% DMSO daily for 60 days. Animals in Group V was orally given 250 µg/kg aflatoxin B1 dissolved in 10% DMSO and 300 mg/kg curcumin dissolved in 10% DMSO daily for 60 days. At the end of the study, erythrocyte count, leukocyte count, platelet count, hemoglobin amount, hematocrit value, percentage ratios of leukocyte types, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) were determined in blood samples taken from all animals. In the study, erythrocytes count, hemoglobin concentration, hematocrit value and MCHC level in the aflatoxin applied rats significantly decreased compared to the control group (p |
| first_indexed | 2024-03-10T03:06:27Z |
| format | Article |
| id | doaj.art-12e85ce8ac4d408d884339bdd0d254d1 |
| institution | Directory Open Access Journal |
| issn | 2147-5652 |
| language | English |
| last_indexed | 2024-03-10T03:06:27Z |
| publishDate | 2020-09-01 |
| publisher | Selcuk University |
| record_format | Article |
| series | Türk Spor ve Egzersiz Dergisi |
| spelling | doaj.art-12e85ce8ac4d408d884339bdd0d254d12023-11-23T10:32:11ZengSelcuk UniversityTürk Spor ve Egzersiz Dergisi2147-56522020-09-01222265270154Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied RatsDeniz Uluışık0Ercan Keskin1Durmuş Hatipoğlu2SELCUK UNIVERSITY, FACULTY OF VETERINARY, DEPARTMENT OF BASIC SCIENCES VETERINARY MEDICINE, DEPARTMENT OF PHYSIOLOGYSELCUK UNIVERSITY, FACULTY OF VETERINARY, DEPARTMENT OF BASIC SCIENCES VETERINARY MEDICINE, DEPARTMENT OF PHYSIOLOGYSELÇUK ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, VETERİNER HEKİMLİĞİ TEMEL BİLİMLERİ BÖLÜMÜ, VETERİNERLİK FİZYOLOJİSİ ANABİLİM DALIIn this study, it is aimed to determine the possible effects of curcumin on hematological parameters in aflatoxin applied rats. Thirty eight healthy male Wistar Albino rats were used in the study. Group I animals was no applied. Animals in Group II were orally given 1 ml 10% DMSO daily for 60 days. Animals in Group III were orally given 300 mg/kg curcumin dissolved in 10% DMSO daily for 60 days. Animals in Group IV were orally given 250 µg/kg aflatoxin B1 dissolved in 10% DMSO daily for 60 days. Animals in Group V was orally given 250 µg/kg aflatoxin B1 dissolved in 10% DMSO and 300 mg/kg curcumin dissolved in 10% DMSO daily for 60 days. At the end of the study, erythrocyte count, leukocyte count, platelet count, hemoglobin amount, hematocrit value, percentage ratios of leukocyte types, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) were determined in blood samples taken from all animals. In the study, erythrocytes count, hemoglobin concentration, hematocrit value and MCHC level in the aflatoxin applied rats significantly decreased compared to the control group (phttps://dergipark.org.tr/tr/download/article-file/1098157aflatoxincurcuminhematological parameters |
| spellingShingle | Deniz Uluışık Ercan Keskin Durmuş Hatipoğlu Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats Türk Spor ve Egzersiz Dergisi aflatoxin curcumin hematological parameters |
| title | Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats |
| title_full | Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats |
| title_fullStr | Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats |
| title_full_unstemmed | Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats |
| title_short | Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats |
| title_sort | effects of curcumin on hematological parameters in aflatoxin b1 applied rats |
| topic | aflatoxin curcumin hematological parameters |
| url | https://dergipark.org.tr/tr/download/article-file/1098157 |
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