Polymorphisms of TP53 gene and its association with colorectal cancer: A case-control investigation

Polymorphisms of TP53 gene and its association with colorectal cancer: A case-control investigation

The tumor suppressor gene (TP53) is crucial for DNA repair mechanism, apoptosis, and cell cycle regulation and progression. In human cancer, TP53 is mutated and highly polymorphic. In the current case-control research investigation, we investigated TP53 gene SNPs, in exonic and intronic regions, as...

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Bibliographic Details
Main Authors: Abdullah M Alhadheq, Narasimha Reddy Parine, Jilani Purusottapatnam Shaik, Rana Alhadheq, Saad Alkahtani, Nada H. Aljarba, Mohammad Alanazi
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of King Saud University: Science
Subjects:
TP53
Genotyping
Cancer
Colorectal
SNP
Polymorphism
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364723003981

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