A Case of Blue Nevus of the Nasal Septum
Blue nevus (BN) is a blue- or black-colored benign melanocytic proliferation that commonly occurs on the dorsal surface of the hands and feet or in the head and neck region. However, BN arising from the sinonasal mucosa is extremely rare. BN is usually asymptomatic and small in size. Based on the pi...
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| Format: | Article |
| Language: | English |
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Korean Rhinologic Society
2021-07-01
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| Series: | Journal of Rhinology |
| Subjects: | |
| Online Access: | http://www.j-rhinology.org/upload/pdf/jr-2021-00345.pdf |
| _version_ | 1818701471791710208 |
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| author | Jun Yong Choi Myoung Su Choi |
| author_facet | Jun Yong Choi Myoung Su Choi |
| author_sort | Jun Yong Choi |
| collection | DOAJ |
| description | Blue nevus (BN) is a blue- or black-colored benign melanocytic proliferation that commonly occurs on the dorsal surface of the hands and feet or in the head and neck region. However, BN arising from the sinonasal mucosa is extremely rare. BN is usually asymptomatic and small in size. Based on the pigmentation of BN, sinonasal malignant melanoma should be considered in the differential diagnosis of BNs in this region. We herein report a case of BN of the nasal septum. Histopathologic examination revealed the presence of heavily pigmented, spindle-shaped melanocytic cells within the stromal tissue. On immunohistochemical analysis, BN cells were positive for S-100 and HMB-45. Due to the few reported cases of sinonasal BN and challenging location, complete resection, biopsy, and adequate follow-up are recommended. |
| first_indexed | 2024-12-17T15:21:22Z |
| format | Article |
| id | doaj.art-12ebeb0aa5774d76a15e2b5f5fb88a24 |
| institution | Directory Open Access Journal |
| issn | 1229-1498 2384-4361 |
| language | English |
| last_indexed | 2024-12-17T15:21:22Z |
| publishDate | 2021-07-01 |
| publisher | Korean Rhinologic Society |
| record_format | Article |
| series | Journal of Rhinology |
| spelling | doaj.art-12ebeb0aa5774d76a15e2b5f5fb88a242022-12-21T21:43:23ZengKorean Rhinologic SocietyJournal of Rhinology1229-14982384-43612021-07-0128210610910.18787/jr.2021.00345710A Case of Blue Nevus of the Nasal SeptumJun Yong Choi0Myoung Su Choi1Department of Otolaryngology-Head and Neck Surgery, Eulji University Medical Cener, Eulji University School of Medicine, Daejeon, KoreaDepartment of Otolaryngology-Head and Neck Surgery, Eulji University Medical Cener, Eulji University School of Medicine, Daejeon, KoreaBlue nevus (BN) is a blue- or black-colored benign melanocytic proliferation that commonly occurs on the dorsal surface of the hands and feet or in the head and neck region. However, BN arising from the sinonasal mucosa is extremely rare. BN is usually asymptomatic and small in size. Based on the pigmentation of BN, sinonasal malignant melanoma should be considered in the differential diagnosis of BNs in this region. We herein report a case of BN of the nasal septum. Histopathologic examination revealed the presence of heavily pigmented, spindle-shaped melanocytic cells within the stromal tissue. On immunohistochemical analysis, BN cells were positive for S-100 and HMB-45. Due to the few reported cases of sinonasal BN and challenging location, complete resection, biopsy, and adequate follow-up are recommended.http://www.j-rhinology.org/upload/pdf/jr-2021-00345.pdfblue nevusmalignant melanomanasal septum |
| spellingShingle | Jun Yong Choi Myoung Su Choi A Case of Blue Nevus of the Nasal Septum Journal of Rhinology blue nevus malignant melanoma nasal septum |
| title | A Case of Blue Nevus of the Nasal Septum |
| title_full | A Case of Blue Nevus of the Nasal Septum |
| title_fullStr | A Case of Blue Nevus of the Nasal Septum |
| title_full_unstemmed | A Case of Blue Nevus of the Nasal Septum |
| title_short | A Case of Blue Nevus of the Nasal Septum |
| title_sort | case of blue nevus of the nasal septum |
| topic | blue nevus malignant melanoma nasal septum |
| url | http://www.j-rhinology.org/upload/pdf/jr-2021-00345.pdf |
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