Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies

In this paper, an SIQR (Susceptible, Infected, Quarantined, Recovered) epidemic model with vaccination, elimination, and quarantine hybrid strategies is proposed, and the dynamics of this model are analyzed by both theoretical and numerical means. Firstly, the basic reproduction number <inline-fo...

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Main Authors: Yanli Ma, Jia-Bao Liu, Haixia Li
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Mathematics
Subjects:
Online Access:https://www.mdpi.com/2227-7390/6/12/328
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author Yanli Ma
Jia-Bao Liu
Haixia Li
author_facet Yanli Ma
Jia-Bao Liu
Haixia Li
author_sort Yanli Ma
collection DOAJ
description In this paper, an SIQR (Susceptible, Infected, Quarantined, Recovered) epidemic model with vaccination, elimination, and quarantine hybrid strategies is proposed, and the dynamics of this model are analyzed by both theoretical and numerical means. Firstly, the basic reproduction number <inline-formula> <math display="inline"> <semantics> <msub> <mi>R</mi> <mn>0</mn> </msub> </semantics> </math> </inline-formula>, which determines whether the disease is extinct or not, is derived. Secondly, by LaSalles invariance principle, it is proved that the disease-free equilibrium is globally asymptotically stable when <inline-formula> <math display="inline"> <semantics> <mrow> <msub> <mi>R</mi> <mn>0</mn> </msub> <mo>&lt;</mo> <mn>1</mn> </mrow> </semantics> </math> </inline-formula>, and the disease dies out. By Routh-Hurwitz criterion theory, we also prove that the disease-free equilibrium is unstable and the unique endemic equilibrium is locally asymptotically stable when <inline-formula> <math display="inline"> <semantics> <mrow> <msub> <mi>R</mi> <mn>0</mn> </msub> <mo>&gt;</mo> <mn>1</mn> </mrow> </semantics> </math> </inline-formula>. Thirdly, by constructing a suitable Lyapunov function, we obtain that the unique endemic equilibrium is globally asymptotically stable and the disease persists at this endemic equilibrium if it initially exists when <inline-formula> <math display="inline"> <semantics> <mrow> <msub> <mi>R</mi> <mn>0</mn> </msub> <mo>&gt;</mo> <mn>1</mn> </mrow> </semantics> </math> </inline-formula>. Finally, some numerical simulations are presented to illustrate the analysis results.
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spelling doaj.art-12f234b196424e1089eba67349c6815e2022-12-22T00:48:40ZengMDPI AGMathematics2227-73902018-12-0161232810.3390/math6120328math6120328Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid StrategiesYanli Ma0Jia-Bao Liu1Haixia Li2Department of General Education, Anhui Xinhua University, Hefei 230088, ChinaSchool of Mathematics and Physics, Anhui Jianzhu University, Hefei 230601, ChinaDepartment of General Education, Anhui Xinhua University, Hefei 230088, ChinaIn this paper, an SIQR (Susceptible, Infected, Quarantined, Recovered) epidemic model with vaccination, elimination, and quarantine hybrid strategies is proposed, and the dynamics of this model are analyzed by both theoretical and numerical means. Firstly, the basic reproduction number <inline-formula> <math display="inline"> <semantics> <msub> <mi>R</mi> <mn>0</mn> </msub> </semantics> </math> </inline-formula>, which determines whether the disease is extinct or not, is derived. Secondly, by LaSalles invariance principle, it is proved that the disease-free equilibrium is globally asymptotically stable when <inline-formula> <math display="inline"> <semantics> <mrow> <msub> <mi>R</mi> <mn>0</mn> </msub> <mo>&lt;</mo> <mn>1</mn> </mrow> </semantics> </math> </inline-formula>, and the disease dies out. By Routh-Hurwitz criterion theory, we also prove that the disease-free equilibrium is unstable and the unique endemic equilibrium is locally asymptotically stable when <inline-formula> <math display="inline"> <semantics> <mrow> <msub> <mi>R</mi> <mn>0</mn> </msub> <mo>&gt;</mo> <mn>1</mn> </mrow> </semantics> </math> </inline-formula>. Thirdly, by constructing a suitable Lyapunov function, we obtain that the unique endemic equilibrium is globally asymptotically stable and the disease persists at this endemic equilibrium if it initially exists when <inline-formula> <math display="inline"> <semantics> <mrow> <msub> <mi>R</mi> <mn>0</mn> </msub> <mo>&gt;</mo> <mn>1</mn> </mrow> </semantics> </math> </inline-formula>. Finally, some numerical simulations are presented to illustrate the analysis results.https://www.mdpi.com/2227-7390/6/12/328basic reproductive numberequilibriumstabilitySIQR epidemic modelvaccinationelimination
spellingShingle Yanli Ma
Jia-Bao Liu
Haixia Li
Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies
Mathematics
basic reproductive number
equilibrium
stability
SIQR epidemic model
vaccination
elimination
title Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies
title_full Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies
title_fullStr Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies
title_full_unstemmed Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies
title_short Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies
title_sort global dynamics of an siqr model with vaccination and elimination hybrid strategies
topic basic reproductive number
equilibrium
stability
SIQR epidemic model
vaccination
elimination
url https://www.mdpi.com/2227-7390/6/12/328
work_keys_str_mv AT yanlima globaldynamicsofansiqrmodelwithvaccinationandeliminationhybridstrategies
AT jiabaoliu globaldynamicsofansiqrmodelwithvaccinationandeliminationhybridstrategies
AT haixiali globaldynamicsofansiqrmodelwithvaccinationandeliminationhybridstrategies