Peptides as carriers of active ingredients: A review

Bioactive compounds are highly valuable in the fields of food and medicine, but their application is limited due to easy deterioration after oral or skin administration. In recent years, the use of peptides as delivery systems for bioactive compounds has been intensively researched because of their...

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Main Authors: Congyi Nie, Yuxiao Zou, Sentai Liao, Qunyu Gao, Qian Li
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Food Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665927123001600
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author Congyi Nie
Yuxiao Zou
Sentai Liao
Qunyu Gao
Qian Li
author_facet Congyi Nie
Yuxiao Zou
Sentai Liao
Qunyu Gao
Qian Li
author_sort Congyi Nie
collection DOAJ
description Bioactive compounds are highly valuable in the fields of food and medicine, but their application is limited due to easy deterioration after oral or skin administration. In recent years, the use of peptides as delivery systems for bioactive compounds has been intensively researched because of their special physicochemical characteristics. Peptides can be assembled using various preparation methods and can form several composite materials such as hydrogels, micelles, emulsions and particles. The composite material properties are determined by peptides, bioactive compounds and the construction methods employed. Herein, this paper provides a comprehensive review of the peptides used for active ingredients delivery, fabrication methods for creating delivery systems, structures, targeting characteristics, functional activities and mechanism of delivery systems, as well as their absorption and metabolism, which provided theoretical basis and reference for further research and development of functional composites.
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spelling doaj.art-12f9e139daf04c3692d707a5683f45e82023-12-12T04:36:04ZengElsevierCurrent Research in Food Science2665-92712023-01-017100592Peptides as carriers of active ingredients: A reviewCongyi Nie0Yuxiao Zou1Sentai Liao2Qunyu Gao3Qian Li4Guangdong Academy of Agricultural Sciences, Sericultural & Agri-Food Research Institute/Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs/Guangdong Key Laboratory of Agricultural Products Processing, Guangzhou, 510610, China; School of Food Science and Engineering, South China University of Technology, Guangzhou, 510640, ChinaGuangdong Academy of Agricultural Sciences, Sericultural & Agri-Food Research Institute/Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs/Guangdong Key Laboratory of Agricultural Products Processing, Guangzhou, 510610, ChinaGuangdong Academy of Agricultural Sciences, Sericultural & Agri-Food Research Institute/Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs/Guangdong Key Laboratory of Agricultural Products Processing, Guangzhou, 510610, ChinaSchool of Food Science and Engineering, South China University of Technology, Guangzhou, 510640, China; Corresponding author.Guangdong Academy of Agricultural Sciences, Sericultural & Agri-Food Research Institute/Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs/Guangdong Key Laboratory of Agricultural Products Processing, Guangzhou, 510610, China; Corresponding author.Bioactive compounds are highly valuable in the fields of food and medicine, but their application is limited due to easy deterioration after oral or skin administration. In recent years, the use of peptides as delivery systems for bioactive compounds has been intensively researched because of their special physicochemical characteristics. Peptides can be assembled using various preparation methods and can form several composite materials such as hydrogels, micelles, emulsions and particles. The composite material properties are determined by peptides, bioactive compounds and the construction methods employed. Herein, this paper provides a comprehensive review of the peptides used for active ingredients delivery, fabrication methods for creating delivery systems, structures, targeting characteristics, functional activities and mechanism of delivery systems, as well as their absorption and metabolism, which provided theoretical basis and reference for further research and development of functional composites.http://www.sciencedirect.com/science/article/pii/S2665927123001600PeptideAbsorptionMetabolismTargeting characteristicFunctional activity
spellingShingle Congyi Nie
Yuxiao Zou
Sentai Liao
Qunyu Gao
Qian Li
Peptides as carriers of active ingredients: A review
Current Research in Food Science
Peptide
Absorption
Metabolism
Targeting characteristic
Functional activity
title Peptides as carriers of active ingredients: A review
title_full Peptides as carriers of active ingredients: A review
title_fullStr Peptides as carriers of active ingredients: A review
title_full_unstemmed Peptides as carriers of active ingredients: A review
title_short Peptides as carriers of active ingredients: A review
title_sort peptides as carriers of active ingredients a review
topic Peptide
Absorption
Metabolism
Targeting characteristic
Functional activity
url http://www.sciencedirect.com/science/article/pii/S2665927123001600
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AT yuxiaozou peptidesascarriersofactiveingredientsareview
AT sentailiao peptidesascarriersofactiveingredientsareview
AT qunyugao peptidesascarriersofactiveingredientsareview
AT qianli peptidesascarriersofactiveingredientsareview