Self-completion method of endoscopic submucosal dissection using the Endosaber for treating colorectal neoplasms (with video)
Abstract Endoscopic submucosal dissection (ESD) is effective for the treatment of colorectal neoplasms. We have developed a self-completion ESD (S-ESD) using Endosaber without requiring additional instruments or assistance. This prospective cohort study was conducted to investigate the feasibility o...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-09792-8 |
| _version_ | 1811272605695475712 |
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| author | Mitsuru Esaki Shun Yamakawa Ryoji Ichijima Sho Suzuki Chika Kusano Hisatomo Ikehara Yosuke Minoda Eikichi Ihara Takuji Gotoda |
| author_facet | Mitsuru Esaki Shun Yamakawa Ryoji Ichijima Sho Suzuki Chika Kusano Hisatomo Ikehara Yosuke Minoda Eikichi Ihara Takuji Gotoda |
| author_sort | Mitsuru Esaki |
| collection | DOAJ |
| description | Abstract Endoscopic submucosal dissection (ESD) is effective for the treatment of colorectal neoplasms. We have developed a self-completion ESD (S-ESD) using Endosaber without requiring additional instruments or assistance. This prospective cohort study was conducted to investigate the feasibility of S-ESD for colorectal neoplasms. Patients with colorectal neoplasms measuring 20–40 mm in size were enrolled. A single operator, without assistance, performed ESD using only the Endosaber. The primary outcome was the success rate of S-ESD. Secondary outcomes included procedure time, the rates of en bloc, complete, and curative resection, and complication rates, including the incidence of perforation and delayed bleeding. In total, 15 patients with 15 lesions were enrolled. The median size of the resected lesions was 28 mm (interquartile range 25–29 mm). S-ESD success rate of 100% was achieved. The median procedure time was 44 min (29.5–53.5 min). We observed en bloc, complete, and curative resection rates of 100%, 93.3%, and 86.7%, respectively, and a complication rate of 6.7% (perforation: 0%, delayed bleeding: 6.7%). S-ESD for colorectal neoplasms was successfully performed with favorable treatment outcomes and low complication rates. S-ESD reduces the number of devices and extent of assistance, making S-ESD a simple and cost-effective procedure. |
| first_indexed | 2024-04-12T22:43:21Z |
| format | Article |
| id | doaj.art-12fbc9ac57ac4b27a1391fabd228ff03 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-12T22:43:21Z |
| publishDate | 2022-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-12fbc9ac57ac4b27a1391fabd228ff032022-12-22T03:13:36ZengNature PortfolioScientific Reports2045-23222022-04-011211910.1038/s41598-022-09792-8Self-completion method of endoscopic submucosal dissection using the Endosaber for treating colorectal neoplasms (with video)Mitsuru Esaki0Shun Yamakawa1Ryoji Ichijima2Sho Suzuki3Chika Kusano4Hisatomo Ikehara5Yosuke Minoda6Eikichi Ihara7Takuji Gotoda8Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of MedicineDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of MedicineDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of MedicineDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of MedicineDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of MedicineDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of MedicineDepartment of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu UniversityDepartment of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu UniversityDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of MedicineAbstract Endoscopic submucosal dissection (ESD) is effective for the treatment of colorectal neoplasms. We have developed a self-completion ESD (S-ESD) using Endosaber without requiring additional instruments or assistance. This prospective cohort study was conducted to investigate the feasibility of S-ESD for colorectal neoplasms. Patients with colorectal neoplasms measuring 20–40 mm in size were enrolled. A single operator, without assistance, performed ESD using only the Endosaber. The primary outcome was the success rate of S-ESD. Secondary outcomes included procedure time, the rates of en bloc, complete, and curative resection, and complication rates, including the incidence of perforation and delayed bleeding. In total, 15 patients with 15 lesions were enrolled. The median size of the resected lesions was 28 mm (interquartile range 25–29 mm). S-ESD success rate of 100% was achieved. The median procedure time was 44 min (29.5–53.5 min). We observed en bloc, complete, and curative resection rates of 100%, 93.3%, and 86.7%, respectively, and a complication rate of 6.7% (perforation: 0%, delayed bleeding: 6.7%). S-ESD for colorectal neoplasms was successfully performed with favorable treatment outcomes and low complication rates. S-ESD reduces the number of devices and extent of assistance, making S-ESD a simple and cost-effective procedure.https://doi.org/10.1038/s41598-022-09792-8 |
| spellingShingle | Mitsuru Esaki Shun Yamakawa Ryoji Ichijima Sho Suzuki Chika Kusano Hisatomo Ikehara Yosuke Minoda Eikichi Ihara Takuji Gotoda Self-completion method of endoscopic submucosal dissection using the Endosaber for treating colorectal neoplasms (with video) Scientific Reports |
| title | Self-completion method of endoscopic submucosal dissection using the Endosaber for treating colorectal neoplasms (with video) |
| title_full | Self-completion method of endoscopic submucosal dissection using the Endosaber for treating colorectal neoplasms (with video) |
| title_fullStr | Self-completion method of endoscopic submucosal dissection using the Endosaber for treating colorectal neoplasms (with video) |
| title_full_unstemmed | Self-completion method of endoscopic submucosal dissection using the Endosaber for treating colorectal neoplasms (with video) |
| title_short | Self-completion method of endoscopic submucosal dissection using the Endosaber for treating colorectal neoplasms (with video) |
| title_sort | self completion method of endoscopic submucosal dissection using the endosaber for treating colorectal neoplasms with video |
| url | https://doi.org/10.1038/s41598-022-09792-8 |
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