A possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo <it>(Bubalus bubalis) </it>in Switzerland
<p>Abstract</p> <p>Background</p> <p>Malignant catarrhal fever (MCF) is a fatal herpesvirus infection, affecting various wild and domestic ruminants all over the world. Water buffaloes were reported to be particularly susceptible for the ovine herpesvirus-2 (OvHV-2) cau...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-12-01
|
| Series: | BMC Veterinary Research |
| Online Access: | http://www.biomedcentral.com/1746-6148/7/78 |
| _version_ | 1818118494701486080 |
|---|---|
| author | Dettwiler Martina Stahel Anina Krüger Sonka Gerspach Christian Braun Ueli Engels Monika Hilbe Monika |
| author_facet | Dettwiler Martina Stahel Anina Krüger Sonka Gerspach Christian Braun Ueli Engels Monika Hilbe Monika |
| author_sort | Dettwiler Martina |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Malignant catarrhal fever (MCF) is a fatal herpesvirus infection, affecting various wild and domestic ruminants all over the world. Water buffaloes were reported to be particularly susceptible for the ovine herpesvirus-2 (OvHV-2) causing the sheep-associated form of MCF (SA-MCF). This report describes the first case of possibly caprine-associated malignant catarrhal fever symptoms in a domestic water buffalo in Switzerland.</p> <p>Case presentation</p> <p>The buffalo cow presented with persistent fever, dyspnoea, nasal bleeding and haematuria. Despite symptomatic therapy, the buffalo died and was submitted to post mortem examination. Major findings were an abomasal ulceration, a mild haemorrhagic cystitis and multifocal haemorrhages on the epicardium and on serosal and mucosal surfaces. Eyes and oral cavity were not affected. Histopathology revealed a mild to moderate lymphohistiocytic vasculitis limited to the brain and the urinary bladder. Although these findings are typical for MCF, OvHV-2 DNA was not detected in peripheral blood lymphocytes or in paraffin-embedded brain, using an OvHV-2 specific real time PCR. With the aid of a panherpesvirus PCR, a caprine herpesvirus-2 (CpHV-2) sequence could be amplified from both samples.</p> <p>Conclusions</p> <p>To our knowledge, this is the first report of malignant catarrhal fever in the subfamily <it>Bovinae</it>, where the presence of CpHV-2 could be demonstrated. The etiological context has yet to be evaluated.</p> |
| first_indexed | 2024-12-11T04:55:12Z |
| format | Article |
| id | doaj.art-12fee41f1b9e4b7f9c3338bbb0d8e5a2 |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-12-11T04:55:12Z |
| publishDate | 2011-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-12fee41f1b9e4b7f9c3338bbb0d8e5a22022-12-22T01:20:17ZengBMCBMC Veterinary Research1746-61482011-12-01717810.1186/1746-6148-7-78A possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo <it>(Bubalus bubalis) </it>in SwitzerlandDettwiler MartinaStahel AninaKrüger SonkaGerspach ChristianBraun UeliEngels MonikaHilbe Monika<p>Abstract</p> <p>Background</p> <p>Malignant catarrhal fever (MCF) is a fatal herpesvirus infection, affecting various wild and domestic ruminants all over the world. Water buffaloes were reported to be particularly susceptible for the ovine herpesvirus-2 (OvHV-2) causing the sheep-associated form of MCF (SA-MCF). This report describes the first case of possibly caprine-associated malignant catarrhal fever symptoms in a domestic water buffalo in Switzerland.</p> <p>Case presentation</p> <p>The buffalo cow presented with persistent fever, dyspnoea, nasal bleeding and haematuria. Despite symptomatic therapy, the buffalo died and was submitted to post mortem examination. Major findings were an abomasal ulceration, a mild haemorrhagic cystitis and multifocal haemorrhages on the epicardium and on serosal and mucosal surfaces. Eyes and oral cavity were not affected. Histopathology revealed a mild to moderate lymphohistiocytic vasculitis limited to the brain and the urinary bladder. Although these findings are typical for MCF, OvHV-2 DNA was not detected in peripheral blood lymphocytes or in paraffin-embedded brain, using an OvHV-2 specific real time PCR. With the aid of a panherpesvirus PCR, a caprine herpesvirus-2 (CpHV-2) sequence could be amplified from both samples.</p> <p>Conclusions</p> <p>To our knowledge, this is the first report of malignant catarrhal fever in the subfamily <it>Bovinae</it>, where the presence of CpHV-2 could be demonstrated. The etiological context has yet to be evaluated.</p>http://www.biomedcentral.com/1746-6148/7/78 |
| spellingShingle | Dettwiler Martina Stahel Anina Krüger Sonka Gerspach Christian Braun Ueli Engels Monika Hilbe Monika A possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo <it>(Bubalus bubalis) </it>in Switzerland BMC Veterinary Research |
| title | A possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo <it>(Bubalus bubalis) </it>in Switzerland |
| title_full | A possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo <it>(Bubalus bubalis) </it>in Switzerland |
| title_fullStr | A possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo <it>(Bubalus bubalis) </it>in Switzerland |
| title_full_unstemmed | A possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo <it>(Bubalus bubalis) </it>in Switzerland |
| title_short | A possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo <it>(Bubalus bubalis) </it>in Switzerland |
| title_sort | possible case of caprine associated malignant catarrhal fever in a domestic water buffalo it bubalus bubalis it in switzerland |
| url | http://www.biomedcentral.com/1746-6148/7/78 |
| work_keys_str_mv | AT dettwilermartina apossiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT stahelanina apossiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT krugersonka apossiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT gerspachchristian apossiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT braunueli apossiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT engelsmonika apossiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT hilbemonika apossiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT dettwilermartina possiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT stahelanina possiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT krugersonka possiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT gerspachchristian possiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT braunueli possiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT engelsmonika possiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland AT hilbemonika possiblecaseofcaprineassociatedmalignantcatarrhalfeverinadomesticwaterbuffaloitbubalusbubalisitinswitzerland |