Developing a Novel Terahertz Fabry–Perot Microcavity Biosensor by Incorporating Porous Film for Yeast Sensing
We present a novel terahertz (THz) Fabry–Perot (FP) microcavity biosensor that uses a porous polytetrafluoroethylene (PTFE) supporting film to improve microorganism detection. The THz FP microcavity confines and enhances fields in the middle of the cavity, where the target microbial film is placed w...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8220/23/13/5797 |
| _version_ | 1827734537074900992 |
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| author | Hwan Sik Kim Seung Won Jun Yeong Hwan Ahn |
| author_facet | Hwan Sik Kim Seung Won Jun Yeong Hwan Ahn |
| author_sort | Hwan Sik Kim |
| collection | DOAJ |
| description | We present a novel terahertz (THz) Fabry–Perot (FP) microcavity biosensor that uses a porous polytetrafluoroethylene (PTFE) supporting film to improve microorganism detection. The THz FP microcavity confines and enhances fields in the middle of the cavity, where the target microbial film is placed with the aid of a PTFE film having a dielectric constant close to unity in the THz range. The resonant frequency shift increased linearly with increasing amount of yeasts, without showing saturation behavior under our experimental conditions. These results agree well with finite-difference time-domain (FDTD) simulations. The sensor’s sensitivity was 11.7 GHz/μm, close to the optimal condition of 12.5 GHz/μm, when yeast was placed at the cavity’s center, but no frequency shift was observed when the yeast was coated on the mirror side. We derived an explicit relation for the frequency shift as a function of the index, amount, and location of the substances that is consistent with the electric field distribution across the cavity. We also produced THz transmission images of yeast-coated PTFE, mapping the frequency shift of the FP resonance and revealing the spatial distribution of yeast. |
| first_indexed | 2024-03-11T01:29:03Z |
| format | Article |
| id | doaj.art-130135983775455e9cc05aeeeee8acf1 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-11T01:29:03Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-130135983775455e9cc05aeeeee8acf12023-11-18T17:26:53ZengMDPI AGSensors1424-82202023-06-012313579710.3390/s23135797Developing a Novel Terahertz Fabry–Perot Microcavity Biosensor by Incorporating Porous Film for Yeast SensingHwan Sik Kim0Seung Won Jun1Yeong Hwan Ahn2Department of Physics and Department of Energy Systems Research, Ajou University, Suwon 16499, Republic of KoreaDepartment of Physics and Department of Energy Systems Research, Ajou University, Suwon 16499, Republic of KoreaDepartment of Physics and Department of Energy Systems Research, Ajou University, Suwon 16499, Republic of KoreaWe present a novel terahertz (THz) Fabry–Perot (FP) microcavity biosensor that uses a porous polytetrafluoroethylene (PTFE) supporting film to improve microorganism detection. The THz FP microcavity confines and enhances fields in the middle of the cavity, where the target microbial film is placed with the aid of a PTFE film having a dielectric constant close to unity in the THz range. The resonant frequency shift increased linearly with increasing amount of yeasts, without showing saturation behavior under our experimental conditions. These results agree well with finite-difference time-domain (FDTD) simulations. The sensor’s sensitivity was 11.7 GHz/μm, close to the optimal condition of 12.5 GHz/μm, when yeast was placed at the cavity’s center, but no frequency shift was observed when the yeast was coated on the mirror side. We derived an explicit relation for the frequency shift as a function of the index, amount, and location of the substances that is consistent with the electric field distribution across the cavity. We also produced THz transmission images of yeast-coated PTFE, mapping the frequency shift of the FP resonance and revealing the spatial distribution of yeast.https://www.mdpi.com/1424-8220/23/13/5797Fabry–Perot cavitymicroorganismsporous film |
| spellingShingle | Hwan Sik Kim Seung Won Jun Yeong Hwan Ahn Developing a Novel Terahertz Fabry–Perot Microcavity Biosensor by Incorporating Porous Film for Yeast Sensing Sensors Fabry–Perot cavity microorganisms porous film |
| title | Developing a Novel Terahertz Fabry–Perot Microcavity Biosensor by Incorporating Porous Film for Yeast Sensing |
| title_full | Developing a Novel Terahertz Fabry–Perot Microcavity Biosensor by Incorporating Porous Film for Yeast Sensing |
| title_fullStr | Developing a Novel Terahertz Fabry–Perot Microcavity Biosensor by Incorporating Porous Film for Yeast Sensing |
| title_full_unstemmed | Developing a Novel Terahertz Fabry–Perot Microcavity Biosensor by Incorporating Porous Film for Yeast Sensing |
| title_short | Developing a Novel Terahertz Fabry–Perot Microcavity Biosensor by Incorporating Porous Film for Yeast Sensing |
| title_sort | developing a novel terahertz fabry perot microcavity biosensor by incorporating porous film for yeast sensing |
| topic | Fabry–Perot cavity microorganisms porous film |
| url | https://www.mdpi.com/1424-8220/23/13/5797 |
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