IL-33 via PKCμ/PRKD1 Mediated α-Catenin Phosphorylation Regulates Endothelial Cell-Barrier Integrity and Ischemia-Induced Vascular Leakage

IL-33 via PKCμ/PRKD1 Mediated α-Catenin Phosphorylation Regulates Endothelial Cell-Barrier Integrity and Ischemia-Induced Vascular Leakage

Angiogenesis, neovascularization, and vascular remodeling are highly dynamic processes, where endothelial cell–cell adhesion within the vessel wall controls a range of physiological processes, such as growth, integrity, and barrier function. The cadherin–catenin adhesion complex is a key contributor...

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Bibliographic Details
Main Authors: Deepti Sharma, Geetika Kaur, Shivantika Bisen, Anamika Sharma, Ahmed S. Ibrahim, Nikhlesh K. Singh
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
adherens junction
PKCμ/PRKD1
proliferative retinopathy
iBRB
vascular leakage
α-catenin
Online Access:https://www.mdpi.com/2073-4409/12/5/703

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