Developmental Changes In Pain And Spinal Immune Gene Expression After Radicular Trauma In The Rat

Developmental Changes In Pain And Spinal Immune Gene Expression After Radicular Trauma In The Rat

Neuropathic pain is an example of chronic pain that develops after nerve injury and is less frequent in infants and children than in adults. Likewise, in animal models of neuropathic pain, allodynia and hyperalgesia are non-existent or attenuated in the infant, with a switch during development by wh...

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Bibliographic Details
Main Authors: Gordon Alfred Barr, Shaoning Wang, Christine L. Weisshaar, Beth A. Winkelstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Neurology
Subjects:
Chemokines
Cytokines
Hyperalgesia
Ontogeny
immune
allodynia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00223/full

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