Tocotrienols as an Anti-Breast Cancer Agent
In the past few years, breast cancer has become the most prevalent type of cancer. The majority of patients receive combinatorial chemotherapy treatments, which may result in increased risk of developing drug resistance, a reduced quality of life, and substantial side effects. Treatment modalities t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Antioxidants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/10/9/1383 |
| _version_ | 1829453508846288896 |
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| author | Madison Trujillo Anupreet Kharbanda Christa Corley Pilar Simmons Antiño R. Allen |
| author_facet | Madison Trujillo Anupreet Kharbanda Christa Corley Pilar Simmons Antiño R. Allen |
| author_sort | Madison Trujillo |
| collection | DOAJ |
| description | In the past few years, breast cancer has become the most prevalent type of cancer. The majority of patients receive combinatorial chemotherapy treatments, which may result in increased risk of developing drug resistance, a reduced quality of life, and substantial side effects. Treatment modalities that could lessen the physical toll of standard treatments or act in synergy with chemotherapeutic treatments would benefit women worldwide. Research into tocotrienols has thus far demonstrated their potential to be such an agent, with tocotrienols surpassing the pharmacological potential of tocopherols. Further research using in vitro and preclinical breast cancer models to support clinical trials is needed. This review uses bibliometric analysis to highlight this gap in research and summarizes the current and future landscape of tocotrienols as an anti-breast cancer agent. |
| first_indexed | 2024-03-10T07:56:46Z |
| format | Article |
| id | doaj.art-13040bcdce784dd5ae3d9c35f611e80b |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-10T07:56:46Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-13040bcdce784dd5ae3d9c35f611e80b2023-11-22T11:47:55ZengMDPI AGAntioxidants2076-39212021-08-01109138310.3390/antiox10091383Tocotrienols as an Anti-Breast Cancer AgentMadison Trujillo0Anupreet Kharbanda1Christa Corley2Pilar Simmons3Antiño R. Allen4Division of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USADepartment of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USADivision of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USADivision of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USADivision of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USAIn the past few years, breast cancer has become the most prevalent type of cancer. The majority of patients receive combinatorial chemotherapy treatments, which may result in increased risk of developing drug resistance, a reduced quality of life, and substantial side effects. Treatment modalities that could lessen the physical toll of standard treatments or act in synergy with chemotherapeutic treatments would benefit women worldwide. Research into tocotrienols has thus far demonstrated their potential to be such an agent, with tocotrienols surpassing the pharmacological potential of tocopherols. Further research using in vitro and preclinical breast cancer models to support clinical trials is needed. This review uses bibliometric analysis to highlight this gap in research and summarizes the current and future landscape of tocotrienols as an anti-breast cancer agent.https://www.mdpi.com/2076-3921/10/9/1383tocotrienolsbreast cancerγ-tocotrienolδ-tocotrienolnatural adjuvantanti-cancer |
| spellingShingle | Madison Trujillo Anupreet Kharbanda Christa Corley Pilar Simmons Antiño R. Allen Tocotrienols as an Anti-Breast Cancer Agent Antioxidants tocotrienols breast cancer γ-tocotrienol δ-tocotrienol natural adjuvant anti-cancer |
| title | Tocotrienols as an Anti-Breast Cancer Agent |
| title_full | Tocotrienols as an Anti-Breast Cancer Agent |
| title_fullStr | Tocotrienols as an Anti-Breast Cancer Agent |
| title_full_unstemmed | Tocotrienols as an Anti-Breast Cancer Agent |
| title_short | Tocotrienols as an Anti-Breast Cancer Agent |
| title_sort | tocotrienols as an anti breast cancer agent |
| topic | tocotrienols breast cancer γ-tocotrienol δ-tocotrienol natural adjuvant anti-cancer |
| url | https://www.mdpi.com/2076-3921/10/9/1383 |
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