Inhibition of sphingolipid metabolism in osteosarcoma protects against CD151-mediated tumorigenicity

Inhibition of sphingolipid metabolism in osteosarcoma protects against CD151-mediated tumorigenicity

Abstract Osteosarcoma is the most common primary bone tumor, with a poor prognosis owing to the lack of efficient molecular-based targeted therapies. Previous studies have suggested an association between CD151 and distinct consequences in osteosarcoma tumorigenicity. However, the potential of CD151...

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Bibliographic Details
Main Authors: Hongsheng Wang, Xinmeng Jin, Yangfeng Zhang, Zhuoying Wang, Tao Zhang, Jing Xu, Jiakang Shen, Pengfei Zan, Mengxiong Sun, Chongren Wang, Yingqi Hua, Xiaojun Ma, Wei Sun
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Cell & Bioscience
Subjects:
Osteosarcoma
Tetraspanin CD151
Sphingolipid metabolism
Target therapy
Online Access:https://doi.org/10.1186/s13578-022-00900-9

Internet

https://doi.org/10.1186/s13578-022-00900-9

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