Underlying mechanisms of disruptive mood dysregulation disorder in children: A systematic review by means of research domain criteria
Abstract Background A systematic overview of underlying mechanisms in the new disruptive mood dysregulation disorder (DMDD) diagnosis is needed. The Research Domain Criteria (RDoC) represent a system of six domains of human functioning, which aims to structure the understanding of the nature of ment...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-03-01
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| Series: | JCPP Advances |
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| Online Access: | https://doi.org/10.1002/jcv2.12060 |
| _version_ | 1818284395743674368 |
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| author | Astrid Brænden Pål Zeiner Marit Coldevin Jan Stubberud Annika Melinder |
| author_facet | Astrid Brænden Pål Zeiner Marit Coldevin Jan Stubberud Annika Melinder |
| author_sort | Astrid Brænden |
| collection | DOAJ |
| description | Abstract Background A systematic overview of underlying mechanisms in the new disruptive mood dysregulation disorder (DMDD) diagnosis is needed. The Research Domain Criteria (RDoC) represent a system of six domains of human functioning, which aims to structure the understanding of the nature of mental illnesses. By means of the RDoC framework, the objective of this systematic review is to synthesize available data on children and youths <18 years suffering from DMDD as reported in peer reviewed papers. Methods A literature search guided by PRISMA was conducted using Medline, PsychInfo, and Embase, while the RDoC domains were employed to systematize research findings. Risk of bias in the included studies was examined. Results We identified 319 studies. After study selection, we included 29 studies. Twenty‐one of these had findings relating to >1 RDoC domain. The risk of bias assessment shows limitations in the research foundation of current knowledge on mechanisms of DMDD. Discussion Reviewing self‐report, behavior and neurocircuit findings by means of RDoC domains, we suggest that DMDD youths have a negative interpretation bias in social processes and valence systems. In occurrence of a negative stimuli interpretation, aberrant cognitive processing may arise. However, current knowledge of DMDD is influenced by lack of sample diversity and open science practices. Conclusion We found the six RDoC domains useful in structuring current evidence of the underlying mechanisms of DMDD. Important opportunities for future studies in this field of research are suggested. In clinical practice, this comprehensive summary on DMDD mechanisms can be used in psychoeducation and treatment plans. |
| first_indexed | 2024-12-13T00:52:08Z |
| format | Article |
| id | doaj.art-1308bba92b9649c1be74883bd3697bec |
| institution | Directory Open Access Journal |
| issn | 2692-9384 |
| language | English |
| last_indexed | 2024-12-13T00:52:08Z |
| publishDate | 2022-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | JCPP Advances |
| spelling | doaj.art-1308bba92b9649c1be74883bd3697bec2022-12-22T00:04:54ZengWileyJCPP Advances2692-93842022-03-0121n/an/a10.1002/jcv2.12060Underlying mechanisms of disruptive mood dysregulation disorder in children: A systematic review by means of research domain criteriaAstrid Brænden0Pål Zeiner1Marit Coldevin2Jan Stubberud3Annika Melinder4Department of Child and Adolescent Psychiatry Oslo University Hospital Oslo NorwayChild and Adolescent Mental Health Research Unit, Department of Research and Innovation Oslo University Hospital Oslo NorwayNic Waals Institute Lovisenberg Diaconal Hospital Oslo NorwayDepartment of Research Lovisenberg Diaconal Hospital Oslo NorwayDepartment of Child and Adolescent Psychiatry Oslo University Hospital Oslo NorwayAbstract Background A systematic overview of underlying mechanisms in the new disruptive mood dysregulation disorder (DMDD) diagnosis is needed. The Research Domain Criteria (RDoC) represent a system of six domains of human functioning, which aims to structure the understanding of the nature of mental illnesses. By means of the RDoC framework, the objective of this systematic review is to synthesize available data on children and youths <18 years suffering from DMDD as reported in peer reviewed papers. Methods A literature search guided by PRISMA was conducted using Medline, PsychInfo, and Embase, while the RDoC domains were employed to systematize research findings. Risk of bias in the included studies was examined. Results We identified 319 studies. After study selection, we included 29 studies. Twenty‐one of these had findings relating to >1 RDoC domain. The risk of bias assessment shows limitations in the research foundation of current knowledge on mechanisms of DMDD. Discussion Reviewing self‐report, behavior and neurocircuit findings by means of RDoC domains, we suggest that DMDD youths have a negative interpretation bias in social processes and valence systems. In occurrence of a negative stimuli interpretation, aberrant cognitive processing may arise. However, current knowledge of DMDD is influenced by lack of sample diversity and open science practices. Conclusion We found the six RDoC domains useful in structuring current evidence of the underlying mechanisms of DMDD. Important opportunities for future studies in this field of research are suggested. In clinical practice, this comprehensive summary on DMDD mechanisms can be used in psychoeducation and treatment plans.https://doi.org/10.1002/jcv2.12060childcomorbiditydisruptive mood dysregulation disorder (DMDD)irritabilitymechanismsRDoC |
| spellingShingle | Astrid Brænden Pål Zeiner Marit Coldevin Jan Stubberud Annika Melinder Underlying mechanisms of disruptive mood dysregulation disorder in children: A systematic review by means of research domain criteria JCPP Advances child comorbidity disruptive mood dysregulation disorder (DMDD) irritability mechanisms RDoC |
| title | Underlying mechanisms of disruptive mood dysregulation disorder in children: A systematic review by means of research domain criteria |
| title_full | Underlying mechanisms of disruptive mood dysregulation disorder in children: A systematic review by means of research domain criteria |
| title_fullStr | Underlying mechanisms of disruptive mood dysregulation disorder in children: A systematic review by means of research domain criteria |
| title_full_unstemmed | Underlying mechanisms of disruptive mood dysregulation disorder in children: A systematic review by means of research domain criteria |
| title_short | Underlying mechanisms of disruptive mood dysregulation disorder in children: A systematic review by means of research domain criteria |
| title_sort | underlying mechanisms of disruptive mood dysregulation disorder in children a systematic review by means of research domain criteria |
| topic | child comorbidity disruptive mood dysregulation disorder (DMDD) irritability mechanisms RDoC |
| url | https://doi.org/10.1002/jcv2.12060 |
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