Thyroid nodule rupture after radiofrequency ablation: case report and literature review
PurposeRadiofrequency ablation (RFA) is an effective and safe modality for the treatment of thyroid nodules. Nodule rupture is a major complication of RFA. There is little known on the natural history of nodule rupture due to a lack of clinical experience and no consensus on its management. A compre...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-04-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1355383/full |
| _version_ | 1827298609090002944 |
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| author | Tatiana Ferraro Tatiana Ferraro Sameeha Sajid Steven P. Hodak Chelsey K. Baldwin |
| author_facet | Tatiana Ferraro Tatiana Ferraro Sameeha Sajid Steven P. Hodak Chelsey K. Baldwin |
| author_sort | Tatiana Ferraro |
| collection | DOAJ |
| description | PurposeRadiofrequency ablation (RFA) is an effective and safe modality for the treatment of thyroid nodules. Nodule rupture is a major complication of RFA. There is little known on the natural history of nodule rupture due to a lack of clinical experience and no consensus on its management. A comprehensive review of nodule rupture presentation, diagnosis, and management is needed.MethodsWe report a case of nodule rupture and conduct a literature review. A total of 33 patients experiencing nodule rupture after RFA were included, and their clinical presentation, management, and outcomes were collected and analyzed.ResultsNodule rupture presents with acute swelling (90.3%) and pain (77.4%) within 7 months of RFA procedure, most commonly due to disruption of the anterior thyroid capsule (87%), and can be diagnosed with ultrasonography. Most ruptures can be managed conservatively, exemplified by our reported case. There are no reported cases of long-term sequalae.ConclusionNodule rupture is the second most common major complication of RFA. Based on the available evidence, we propose a treatment algorithm for nodule rupture and recommendations for future data collection to address gaps in our understanding of rupture etiology and effective management. |
| first_indexed | 2024-04-24T15:17:47Z |
| format | Article |
| id | doaj.art-1308f1772fc74494837f63db0445bbbe |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-24T15:17:47Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-1308f1772fc74494837f63db0445bbbe2024-04-02T08:48:10ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922024-04-011510.3389/fendo.2024.13553831355383Thyroid nodule rupture after radiofrequency ablation: case report and literature reviewTatiana Ferraro0Tatiana Ferraro1Sameeha Sajid2Steven P. Hodak3Chelsey K. Baldwin4Division of Otolaryngology-Head and Neck Surgery, The George Washington University School of Medicine and Health Sciences, Washington, DC, United StatesDepartment of Endocrinology, The George Washington University School of Medicine & Health Sciences, Washington, DC, United StatesDepartment of Endocrinology, The George Washington University School of Medicine & Health Sciences, Washington, DC, United StatesDepartment of Medicine, Diabetes and Endocrinology Section, New York University School of Medicine, New York, NY, United StatesDepartment of Medicine, Diabetes and Endocrinology Section, New York University School of Medicine, New York, NY, United StatesPurposeRadiofrequency ablation (RFA) is an effective and safe modality for the treatment of thyroid nodules. Nodule rupture is a major complication of RFA. There is little known on the natural history of nodule rupture due to a lack of clinical experience and no consensus on its management. A comprehensive review of nodule rupture presentation, diagnosis, and management is needed.MethodsWe report a case of nodule rupture and conduct a literature review. A total of 33 patients experiencing nodule rupture after RFA were included, and their clinical presentation, management, and outcomes were collected and analyzed.ResultsNodule rupture presents with acute swelling (90.3%) and pain (77.4%) within 7 months of RFA procedure, most commonly due to disruption of the anterior thyroid capsule (87%), and can be diagnosed with ultrasonography. Most ruptures can be managed conservatively, exemplified by our reported case. There are no reported cases of long-term sequalae.ConclusionNodule rupture is the second most common major complication of RFA. Based on the available evidence, we propose a treatment algorithm for nodule rupture and recommendations for future data collection to address gaps in our understanding of rupture etiology and effective management.https://www.frontiersin.org/articles/10.3389/fendo.2024.1355383/fullradiofrequency ablationthyroid nodule ruptureminimally invasive techniquesthermal ablationthyroid nodule |
| spellingShingle | Tatiana Ferraro Tatiana Ferraro Sameeha Sajid Steven P. Hodak Chelsey K. Baldwin Thyroid nodule rupture after radiofrequency ablation: case report and literature review Frontiers in Endocrinology radiofrequency ablation thyroid nodule rupture minimally invasive techniques thermal ablation thyroid nodule |
| title | Thyroid nodule rupture after radiofrequency ablation: case report and literature review |
| title_full | Thyroid nodule rupture after radiofrequency ablation: case report and literature review |
| title_fullStr | Thyroid nodule rupture after radiofrequency ablation: case report and literature review |
| title_full_unstemmed | Thyroid nodule rupture after radiofrequency ablation: case report and literature review |
| title_short | Thyroid nodule rupture after radiofrequency ablation: case report and literature review |
| title_sort | thyroid nodule rupture after radiofrequency ablation case report and literature review |
| topic | radiofrequency ablation thyroid nodule rupture minimally invasive techniques thermal ablation thyroid nodule |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2024.1355383/full |
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