Sarcoid-like reaction associated with renal cell carcinoma – A case report
Renal cell carcinoma (RCC) is a highly vascular tumor, which may spread to the lungs and other organs. It often presents with localized or systemic manifestation, including paraneoplastic syndromes. Sarcoidosis is a systemic granulomatous inflammatory disease characterized by non-caseating granuloma...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-01-01
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| Series: | Respiratory Medicine Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007119300735 |
| _version_ | 1818059830671179776 |
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| author | Asma Iftikhar Muhammad A.I. Cheema Preethi Ramachandran Sonu Sahni |
| author_facet | Asma Iftikhar Muhammad A.I. Cheema Preethi Ramachandran Sonu Sahni |
| author_sort | Asma Iftikhar |
| collection | DOAJ |
| description | Renal cell carcinoma (RCC) is a highly vascular tumor, which may spread to the lungs and other organs. It often presents with localized or systemic manifestation, including paraneoplastic syndromes. Sarcoidosis is a systemic granulomatous inflammatory disease characterized by non-caseating granulomas that typically afflicts the respiratory system. In the absence of any evidence of systemic sarcoidosis they are referred to as sarcoid-like reactions. Non-caseating epithelioid granulomas, also regarded to sarcoid-like granulomas have been described in association with certain malignancies such as carcinomas of the breast, colon, seminoma, and Hodgkin's lymphoma. However, sarcoid like reaction associated with renal cell carcinoma is uncommon. Herein we present a rare case of a patient with renal cell carcinoma with mediastinal lymphadenopathy initially thought to metastatic disease, though revealed a sarcoid-like reaction with review of literature. Keywords: Renal cell carcinoma, Sarcoid like reaction, Paraneoplastic syndrome, Metastatic disease |
| first_indexed | 2024-12-10T13:22:46Z |
| format | Article |
| id | doaj.art-130b151adcec4e34a58590825bce243e |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-12-10T13:22:46Z |
| publishDate | 2019-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-130b151adcec4e34a58590825bce243e2022-12-22T01:47:16ZengElsevierRespiratory Medicine Case Reports2213-00712019-01-0127Sarcoid-like reaction associated with renal cell carcinoma – A case reportAsma Iftikhar0Muhammad A.I. Cheema1Preethi Ramachandran2Sonu Sahni3New York - Presbyterian Queens, Division of Pulmonary, Critical Care and Sleep Medicine, Flushing, NY, 11355, USANew York - Presbyterian Queens, Division of Pulmonary, Critical Care and Sleep Medicine, Flushing, NY, 11355, USABrookdale University Hospital Medical Center, Division of Hematology and Oncology, Brooklyn, NY, 11212, USABrookdale University Hospital Medical Center, Department of Internal Medicine, Brooklyn, NY, 11212, USA; Touro College of Osteopathic Medicine, Department of Primary Care, New York, NY, 10027, USA; Corresponding author. Brookdale University Hospital Medical Center, Department of Internal Medicine, Brooklyn, NY, 11212, USA.Renal cell carcinoma (RCC) is a highly vascular tumor, which may spread to the lungs and other organs. It often presents with localized or systemic manifestation, including paraneoplastic syndromes. Sarcoidosis is a systemic granulomatous inflammatory disease characterized by non-caseating granulomas that typically afflicts the respiratory system. In the absence of any evidence of systemic sarcoidosis they are referred to as sarcoid-like reactions. Non-caseating epithelioid granulomas, also regarded to sarcoid-like granulomas have been described in association with certain malignancies such as carcinomas of the breast, colon, seminoma, and Hodgkin's lymphoma. However, sarcoid like reaction associated with renal cell carcinoma is uncommon. Herein we present a rare case of a patient with renal cell carcinoma with mediastinal lymphadenopathy initially thought to metastatic disease, though revealed a sarcoid-like reaction with review of literature. Keywords: Renal cell carcinoma, Sarcoid like reaction, Paraneoplastic syndrome, Metastatic diseasehttp://www.sciencedirect.com/science/article/pii/S2213007119300735 |
| spellingShingle | Asma Iftikhar Muhammad A.I. Cheema Preethi Ramachandran Sonu Sahni Sarcoid-like reaction associated with renal cell carcinoma – A case report Respiratory Medicine Case Reports |
| title | Sarcoid-like reaction associated with renal cell carcinoma – A case report |
| title_full | Sarcoid-like reaction associated with renal cell carcinoma – A case report |
| title_fullStr | Sarcoid-like reaction associated with renal cell carcinoma – A case report |
| title_full_unstemmed | Sarcoid-like reaction associated with renal cell carcinoma – A case report |
| title_short | Sarcoid-like reaction associated with renal cell carcinoma – A case report |
| title_sort | sarcoid like reaction associated with renal cell carcinoma a case report |
| url | http://www.sciencedirect.com/science/article/pii/S2213007119300735 |
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