Bone Morphogenetic Protein-4 Impairs Retinal Endothelial Cell Barrier, a Potential Role in Diabetic Retinopathy

Bone Morphogenetic Protein-4 Impairs Retinal Endothelial Cell Barrier, a Potential Role in Diabetic Retinopathy

Bone Morphogenetic Protein 4 (BMP4) is a secreted growth factor of the Transforming Growth Factor beta (TGFβ) superfamily. The goal of this study was to test whether BMP4 contributes to the pathogenesis of diabetic retinopathy (DR). Immunofluorescence of BMP4 and the vascular marker isolectin-B4 was...

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Bibliographic Details
Main Authors:	Noureldien H. E. Darwish, Khaled A. Hussein, Khaled Elmasry, Ahmed S. Ibrahim, Julia Humble, Mohamed Moustafa, Fatma Awadalla, Mohamed Al-Shabrawey
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	Cells
Subjects:	bone morphogenetic proteins BMP4 Smad1/5/9 diabetic retinopathy blood–retinal barrier function
Online Access:	https://www.mdpi.com/2073-4409/12/9/1279

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