Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems

Abstract Significant progress on upconversion‐nanoparticle (UCNP)‐based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non‐autofluorescence, high chemical stability...

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Main Authors: Bin Gu, Qichun Zhang
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.201700609
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author Bin Gu
Qichun Zhang
author_facet Bin Gu
Qichun Zhang
author_sort Bin Gu
collection DOAJ
description Abstract Significant progress on upconversion‐nanoparticle (UCNP)‐based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non‐autofluorescence, high chemical stability, large light‐penetration depth, long lifetime, and less damage to samples. This article focuses on recent achievements in the usage of lanthanide‐doped UCNPs as efficient probes for biodetection since 2014. The mechanisms of upconversion as well as the luminescence resonance energy transfer process is introduced first, followed by a detailed summary on the recent researches of UCNP‐based biodetections including the detection of inorganic ions, gas molecules, reactive oxygen species, and thiols and hydrogen sulfide.
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spelling doaj.art-130cfe4c562543bba9a8948bbb714ffa2022-12-21T18:52:36ZengWileyAdvanced Science2198-38442018-03-0153n/an/a10.1002/advs.201700609Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in BiosystemsBin Gu0Qichun Zhang1School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 SingaporeSchool of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 SingaporeAbstract Significant progress on upconversion‐nanoparticle (UCNP)‐based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non‐autofluorescence, high chemical stability, large light‐penetration depth, long lifetime, and less damage to samples. This article focuses on recent achievements in the usage of lanthanide‐doped UCNPs as efficient probes for biodetection since 2014. The mechanisms of upconversion as well as the luminescence resonance energy transfer process is introduced first, followed by a detailed summary on the recent researches of UCNP‐based biodetections including the detection of inorganic ions, gas molecules, reactive oxygen species, and thiols and hydrogen sulfide.https://doi.org/10.1002/advs.201700609biodetectionenergy acceptorionssmall moleculesupconversion
spellingShingle Bin Gu
Qichun Zhang
Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems
Advanced Science
biodetection
energy acceptor
ions
small molecules
upconversion
title Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems
title_full Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems
title_fullStr Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems
title_full_unstemmed Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems
title_short Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems
title_sort recent advances on functionalized upconversion nanoparticles for detection of small molecules and ions in biosystems
topic biodetection
energy acceptor
ions
small molecules
upconversion
url https://doi.org/10.1002/advs.201700609
work_keys_str_mv AT bingu recentadvancesonfunctionalizedupconversionnanoparticlesfordetectionofsmallmoleculesandionsinbiosystems
AT qichunzhang recentadvancesonfunctionalizedupconversionnanoparticlesfordetectionofsmallmoleculesandionsinbiosystems