Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems
Abstract Significant progress on upconversion‐nanoparticle (UCNP)‐based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non‐autofluorescence, high chemical stability...
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Format: | Article |
Language: | English |
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Wiley
2018-03-01
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Series: | Advanced Science |
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Online Access: | https://doi.org/10.1002/advs.201700609 |
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author | Bin Gu Qichun Zhang |
author_facet | Bin Gu Qichun Zhang |
author_sort | Bin Gu |
collection | DOAJ |
description | Abstract Significant progress on upconversion‐nanoparticle (UCNP)‐based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non‐autofluorescence, high chemical stability, large light‐penetration depth, long lifetime, and less damage to samples. This article focuses on recent achievements in the usage of lanthanide‐doped UCNPs as efficient probes for biodetection since 2014. The mechanisms of upconversion as well as the luminescence resonance energy transfer process is introduced first, followed by a detailed summary on the recent researches of UCNP‐based biodetections including the detection of inorganic ions, gas molecules, reactive oxygen species, and thiols and hydrogen sulfide. |
first_indexed | 2024-12-21T19:36:11Z |
format | Article |
id | doaj.art-130cfe4c562543bba9a8948bbb714ffa |
institution | Directory Open Access Journal |
issn | 2198-3844 |
language | English |
last_indexed | 2024-12-21T19:36:11Z |
publishDate | 2018-03-01 |
publisher | Wiley |
record_format | Article |
series | Advanced Science |
spelling | doaj.art-130cfe4c562543bba9a8948bbb714ffa2022-12-21T18:52:36ZengWileyAdvanced Science2198-38442018-03-0153n/an/a10.1002/advs.201700609Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in BiosystemsBin Gu0Qichun Zhang1School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 SingaporeSchool of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 SingaporeAbstract Significant progress on upconversion‐nanoparticle (UCNP)‐based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non‐autofluorescence, high chemical stability, large light‐penetration depth, long lifetime, and less damage to samples. This article focuses on recent achievements in the usage of lanthanide‐doped UCNPs as efficient probes for biodetection since 2014. The mechanisms of upconversion as well as the luminescence resonance energy transfer process is introduced first, followed by a detailed summary on the recent researches of UCNP‐based biodetections including the detection of inorganic ions, gas molecules, reactive oxygen species, and thiols and hydrogen sulfide.https://doi.org/10.1002/advs.201700609biodetectionenergy acceptorionssmall moleculesupconversion |
spellingShingle | Bin Gu Qichun Zhang Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems Advanced Science biodetection energy acceptor ions small molecules upconversion |
title | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
title_full | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
title_fullStr | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
title_full_unstemmed | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
title_short | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
title_sort | recent advances on functionalized upconversion nanoparticles for detection of small molecules and ions in biosystems |
topic | biodetection energy acceptor ions small molecules upconversion |
url | https://doi.org/10.1002/advs.201700609 |
work_keys_str_mv | AT bingu recentadvancesonfunctionalizedupconversionnanoparticlesfordetectionofsmallmoleculesandionsinbiosystems AT qichunzhang recentadvancesonfunctionalizedupconversionnanoparticlesfordetectionofsmallmoleculesandionsinbiosystems |