Dilated cardiomyopathy in patients with hypoparathyroidism: A narrative review
Abstract Background Hypoparathyroidism is a rare endocrine disorder characterized by low blood calcium levels, elevated phosphorus levels, and insufficient parathyroid hormone production. It can lead to dilated cardiomyopathy (DCM), a cardiac condition characterized by enlarged ventricles and reduce...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Health Science Reports |
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| Online Access: | https://doi.org/10.1002/hsr2.1796 |
| _version_ | 1797331668309114880 |
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| author | Maryam Abdolmaleki Laya Ohadi Saba Maleki |
| author_facet | Maryam Abdolmaleki Laya Ohadi Saba Maleki |
| author_sort | Maryam Abdolmaleki |
| collection | DOAJ |
| description | Abstract Background Hypoparathyroidism is a rare endocrine disorder characterized by low blood calcium levels, elevated phosphorus levels, and insufficient parathyroid hormone production. It can lead to dilated cardiomyopathy (DCM), a cardiac condition characterized by enlarged ventricles and reduced heart function. This review aims to explore the relationship between hypoparathyroidism and DCM, the impact of calcium on cardiac function, and the potential for DCM reversal with calcium supplementation. Methods A comprehensive literature search was conducted using PubMed, Google Scholar, and relevant keywords and Mesh terms. Case reports evaluating dilated cardiomyopathy in patients with Hypoparathyroidism were included in the study. Additionally, references cited in each study were carefully examined to identify relevant reports. The cases included in the review were analyzed, and common cardiac manifestations, diagnostic approaches, and management were identified. Results DCM in hypoparathyroidism presents with symptoms of heart failure, reduced ejection fraction, and impaired left ventricular function. Laboratory tests show low serum calcium levels and elevated phosphate levels. Prompt diagnosis and treatment with calcium and vitamin D supplementation can lead to improvements in cardiac function. Conclusion Hypoparathyroidism‐induced DCM is reversible with timely calcium and vitamin D supplementation. Patient compliance with prescribed medications and supplements is crucial to prevent and manage cardiac complications. Regular follow‐up check‐ups and monitoring of calcium levels can aid in early detection and improve patient outcomes. Educating patients about the importance of treatment adherence can significantly reduce the risk of developing DCM and other cardiac symptoms associated with hypoparathyroidism. Routine follow‐up of DCM among patients with endocrine disorders is recommended. |
| first_indexed | 2024-03-08T07:37:47Z |
| format | Article |
| id | doaj.art-130dc820f2f246da931cd5b695da0a12 |
| institution | Directory Open Access Journal |
| issn | 2398-8835 |
| language | English |
| last_indexed | 2024-03-08T07:37:47Z |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj.art-130dc820f2f246da931cd5b695da0a122024-02-02T18:04:59ZengWileyHealth Science Reports2398-88352024-01-0171n/an/a10.1002/hsr2.1796Dilated cardiomyopathy in patients with hypoparathyroidism: A narrative reviewMaryam Abdolmaleki0Laya Ohadi1Saba Maleki2Shahid Beheshti University of Medical Sciences Tehran IranShahid Beheshti University of Medical Sciences Tehran IranSchool of Medicine Guilan University of Medical Sciences Rasht IranAbstract Background Hypoparathyroidism is a rare endocrine disorder characterized by low blood calcium levels, elevated phosphorus levels, and insufficient parathyroid hormone production. It can lead to dilated cardiomyopathy (DCM), a cardiac condition characterized by enlarged ventricles and reduced heart function. This review aims to explore the relationship between hypoparathyroidism and DCM, the impact of calcium on cardiac function, and the potential for DCM reversal with calcium supplementation. Methods A comprehensive literature search was conducted using PubMed, Google Scholar, and relevant keywords and Mesh terms. Case reports evaluating dilated cardiomyopathy in patients with Hypoparathyroidism were included in the study. Additionally, references cited in each study were carefully examined to identify relevant reports. The cases included in the review were analyzed, and common cardiac manifestations, diagnostic approaches, and management were identified. Results DCM in hypoparathyroidism presents with symptoms of heart failure, reduced ejection fraction, and impaired left ventricular function. Laboratory tests show low serum calcium levels and elevated phosphate levels. Prompt diagnosis and treatment with calcium and vitamin D supplementation can lead to improvements in cardiac function. Conclusion Hypoparathyroidism‐induced DCM is reversible with timely calcium and vitamin D supplementation. Patient compliance with prescribed medications and supplements is crucial to prevent and manage cardiac complications. Regular follow‐up check‐ups and monitoring of calcium levels can aid in early detection and improve patient outcomes. Educating patients about the importance of treatment adherence can significantly reduce the risk of developing DCM and other cardiac symptoms associated with hypoparathyroidism. Routine follow‐up of DCM among patients with endocrine disorders is recommended.https://doi.org/10.1002/hsr2.1796calcium levelcalcium supplementationdilated cardiomyopathyhypoparathyroidism |
| spellingShingle | Maryam Abdolmaleki Laya Ohadi Saba Maleki Dilated cardiomyopathy in patients with hypoparathyroidism: A narrative review Health Science Reports calcium level calcium supplementation dilated cardiomyopathy hypoparathyroidism |
| title | Dilated cardiomyopathy in patients with hypoparathyroidism: A narrative review |
| title_full | Dilated cardiomyopathy in patients with hypoparathyroidism: A narrative review |
| title_fullStr | Dilated cardiomyopathy in patients with hypoparathyroidism: A narrative review |
| title_full_unstemmed | Dilated cardiomyopathy in patients with hypoparathyroidism: A narrative review |
| title_short | Dilated cardiomyopathy in patients with hypoparathyroidism: A narrative review |
| title_sort | dilated cardiomyopathy in patients with hypoparathyroidism a narrative review |
| topic | calcium level calcium supplementation dilated cardiomyopathy hypoparathyroidism |
| url | https://doi.org/10.1002/hsr2.1796 |
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