PreCanCell: An ensemble learning algorithm for predicting cancer and non-cancer cells from single-cell transcriptomes

PreCanCell: An ensemble learning algorithm for predicting cancer and non-cancer cells from single-cell transcriptomes

We propose PreCanCell, a novel algorithm for predicting malignant and non-malignant cells from single-cell transcriptomes. PreCanCell first identifies the differentially expressed genes (DEGs) between malignant and non-malignant cells commonly in five common cancer types-associated single-cell trans...

Full description

Bibliographic Details
Main Authors:	Tao Yang, Qiyu Yan, Rongzhuo Long, Zhixian Liu, Xiaosheng Wang
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Series:	Computational and Structural Biotechnology Journal
Subjects:	Ensemble learning algorithm Single-cell transcriptomes Cancer and non-cancer cells Tumor marker genes Non-tumor marker genes
Online Access:	http://www.sciencedirect.com/science/article/pii/S200103702300243X

Similar Items

Correlation of serum tumor markers and incidence of driver gene mutations in non-small cell lung cancer
by: ZHU Mengxiao, et al.
Published: (2022-12-01)

Combined detection of aneuploid circulating tumor‐derived endothelial cells and circulating tumor cells may improve diagnosis of early stage non‐small‐cell lung cancer
by: Yuanyuan Lei, et al.
Published: (2020-07-01)

The Indicative Value of Serum Tumor Markers for Metastasis and Stage of Non-Small Cell Lung Cancer
by: Chunyang Jiang, et al.
Published: (2022-10-01)

Plasticity in Colorectal Cancer: Why Cancer Cells Differentiate
by: Romina Judith Walter, et al.
Published: (2021-02-01)

Usage patterns of biomarkers in non-small-cell lung cancer patients in India: Findings from a systematic review and survey
by: Chirag Desai, et al.
Published: (2014-01-01)

Investigating gene expression profile of non-small cell lung cancer
by: Vooder Tõnu, et al.
Published: (2011-10-01)

Contribution of endothelial cell-derived transcriptomes to the colon cancer based on bioinformatics analysis
by: Jie Wang, et al.
Published: (2021-08-01)

Construction of a B cell-related gene pairs signature for predicting prognosis and immunotherapeutic response in non-small cell lung cancer
by: Xuanzong Li, et al.
Published: (2022-10-01)

gef Gene Expression in MCF-7 Breast Cancer Cells is Associated with a Better Prognosis and Induction of Apoptosis by p53-Mediated Signaling Pathway
by: Antonia Aránega, et al.
Published: (2011-10-01)

Identification of Cancer Cells in the Human Body by Anti-Telomerase Peptide Antibody: Towards the Isolation of Circulating Tumor Cells
by: Olga Karpov, et al.
Published: (2022-10-01)

Clinical applications of circulating tumor cells in lung cancer patients by CellSearch system
by: Anna eTruini, et al.
Published: (2014-09-01)

Editorial: The cross-talk between cancer cells and immune cells in the tumor microenvironment
by: Tao Li, et al.
Published: (2023-11-01)

Colon Cancer-Related Genes Identification and Function Study Based on Single-Cell Multi-Omics Integration
by: Xuepu Sun, et al.
Published: (2021-11-01)

Cancer Stem Cell-Like Circulating Tumor Cells Are Prognostic in Non-Small Cell Lung Cancer
by: Eva Obermayr, et al.
Published: (2021-11-01)

HE4 Gene Overexpression in Ovarian Cancer
by: A Shahi, et al.
Published: (2016-03-01)

Cancer Epidemiology, Biomarkers & Prevention
by: American Society of Preventive Oncology
Published: (1991)

Expression of Multiple Cancer/Testis Genes in Several Breast Cancer Cell Lines
by: Shamseddin Yousef-Amoli, et al.
Published: (2014-04-01)

Lung Cancers: Molecular Characterization, Clonal Heterogeneity and Evolution, and Cancer Stem Cells
by: Ugo Testa, et al.
Published: (2018-07-01)

Risk score = LncRNAs associated with doxorubicin metabolism can be used as molecular markers for immune microenvironment and immunotherapy in non-small cell lung cancer
by: Qianyi Lin, et al.
Published: (2023-03-01)

Genomic and serum tumor markers in Egyptian females with and without family cancer history
by: H. Salem, et al.
Published: (2022-07-01)

Ovarian Cancer and Cancer Stem Cells—Cellular and Molecular Characteristics, Signaling Pathways, and Usefulness as a Diagnostic Tool in Medicine and Oncology
by: Andrzej Nowicki, et al.
Published: (2021-08-01)

Use of Single Cell Transcriptomic Techniques to Study the Role of High-Risk Human Papillomavirus Infection in Cervical Cancer
by: Lingzhang Meng, et al.
Published: (2022-06-01)

Development and clinical validation of a seven-gene signature based on tumor stem cell-related genes to predict ovarian cancer prognosis
by: Guangwei Wang, et al.
Published: (2024-03-01)

Single-Cell Transcriptomics of Immune Cells Reveal Diversity and Exhaustion Signatures in Non-Small-Cell Lung Cancer
by: Ying Zhao, et al.
Published: (2022-07-01)

Comparison of RNA Marker Panels for Circulating Tumor Cells and Evaluation of Their Prognostic Relevance in Breast Cancer
by: Eva Welsch, et al.
Published: (2023-02-01)

The Genes—Candidates for Prognostic Markers of Metastasis by Expression Level in Clear Cell Renal Cell Cancer
by: Natalya Apanovich, et al.
Published: (2020-01-01)

Cancer biomarkers : minimal and noninvasive early diagnosis and prognosis /
by: Barh, Debmalya, editor, et al.
Published: (2014)

TUMOR-RELATED METHYLATED CELL-FREE DNA AND CIRCULATING TUMOR CELLS IN MELANOMA
by: Francesca eSalvianti, et al.
Published: (2016-01-01)

Single-cell and spatial heterogeneity landscapes of mature epicardial cells
by: Jianlin Du, et al.
Published: (2023-08-01)

Liquid Biopsy-Based Colorectal Cancer Screening via Surface Markers of Circulating Tumor Cells
by: Francis Yew Fu Tieng, et al.
Published: (2021-11-01)

Cancer-Cell-Derived IgG and Its Potential Role in Tumor Development
by: Said Kdimati, et al.
Published: (2021-10-01)

The rational application of liquid biopsy based on next‐generation sequencing in advanced non‐small cell lung cancer
by: Chenglong Zhao, et al.
Published: (2023-03-01)

Prospective Monitoring of Circulating Epithelial Tumor Cells (CETC) Reveals Changes in Gene Expression during Adjuvant Radiotherapy of Breast Cancer Patients
by: Matthias Mäurer, et al.
Published: (2021-09-01)

Transcriptome-Based Traits of Radioresistant Sublines of Non-Small Cell Lung Cancer Cells
by: Margarita Pustovalova, et al.
Published: (2023-02-01)

A tumor microenvironment gene set–Based prognostic signature for non-small-cell lung cancer
by: Yingsheng Wen, et al.
Published: (2022-08-01)

Identification of novel membrane markers in circulating tumor cells of mesenchymal state in breast cancer
by: Yongdeuk Hwang, et al.
Published: (2024-07-01)

Single-cell and transcriptomic analyses reveal the influence of diabetes on ovarian cancer
by: Zhihao Zhao, et al.
Published: (2024-01-01)

Difference of serum tumor markers in different clinical stages of elderly patients with non-small cell lung cancer and evaluation of diagnostic value
by: Qin Wen Wen, et al.
Published: (2023-01-01)

Tumor marker for colorectal cancer
by: Sopon Jutiamornlert, et al.
Published: (2010-04-01)

Ensemble learning for detecting gene-gene interactions in colorectal cancer
by: Faramarz Dorani, et al.
Published: (2018-10-01)