MRE11 Is Crucial for Malaria Parasite Transmission and Its Absence Affects Expression of Interconnected Networks of Key Genes Essential for Life

MRE11 Is Crucial for Malaria Parasite Transmission and Its Absence Affects Expression of Interconnected Networks of Key Genes Essential for Life

The meiotic recombination 11 protein (MRE11) plays a key role in DNA damage response and maintenance of genome stability. However, little is known about its function during development of the malaria parasite <i>Plasmodium</i>. Here, we present a functional, ultrastructural and transcrip...

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Bibliographic Details
Main Authors: David S. Guttery, Abhinay Ramaprasad, David J. P. Ferguson, Mohammad Zeeshan, Rajan Pandey, Declan Brady, Anthony A. Holder, Arnab Pain, Rita Tewari
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
<i>Plasmodium</i>
DNA repair
MRE11
malaria
ribogenesis
Online Access:https://www.mdpi.com/2073-4409/9/12/2590

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