The Effect of Cefovecin Sodium in Shelter Dogs with Bacterial Lower Respiratory Disease
Abstract This study evaluated the clinical and bacteriological efficacy of cefovecin sodium in shelter dogs with bacterial lower respiratory disease. All dogs (n = 32) with lower respiratory disease were divided into two treatment groups: the cefovecin (n = 16) and the ceftriaxone (n = 16) groups. O...
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| Format: | Article |
| Language: | English |
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Instituto de Tecnologia do Paraná (Tecpar)
2023-08-01
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| Series: | Brazilian Archives of Biology and Technology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100321&tlng=en |
| _version_ | 1797751899659698176 |
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| author | Serkan İrfan Köse Burçin Özer Ramazan Gönenci Zafer Cantekin |
| author_facet | Serkan İrfan Köse Burçin Özer Ramazan Gönenci Zafer Cantekin |
| author_sort | Serkan İrfan Köse |
| collection | DOAJ |
| description | Abstract This study evaluated the clinical and bacteriological efficacy of cefovecin sodium in shelter dogs with bacterial lower respiratory disease. All dogs (n = 32) with lower respiratory disease were divided into two treatment groups: the cefovecin (n = 16) and the ceftriaxone (n = 16) groups. On the first five days and the 8th day of treatment, and after treatment (15th day), the examination of all dogs was performed. Blood analysis and thoracic radiographic imaging were done. In bronchoalveolar lavage fluids, in the cefovecin group, Bordetella bronchiseptica (n=13), Staphylococcus spp. (n=9), Streptococcus spp. (n=7), Klebsiella pneumonia (n=1); in the ceftriaxone group; B. bronchiseptica (n=5), Escherichia coli (n=5), Pasteurella canis (n=4), Streptococcus spp. (n=3), Staphylococcus aureus (n=1), Pasteurella aerogenes (n=1) and Klebsiella oxytoca (n=1) were isolated and identified. Cefovecin and ceftriaxone sodium treatment protocols had anti-bacterial efficacies of 68.75% and 100%, respectively. In light of the study results, it is concluded that although cefovecin sodium looks to be an antibacterial drug that may be used to treat bacterial lower respiratory tract infections in shelter dogs due to its ease of use, cefovecin and other cephalosporins should not be used empirically as they may contribute to bacterial resistance. |
| first_indexed | 2024-03-12T16:55:19Z |
| format | Article |
| id | doaj.art-131248ec80ec404fbce3429df141841c |
| institution | Directory Open Access Journal |
| issn | 1678-4324 |
| language | English |
| last_indexed | 2024-03-12T16:55:19Z |
| publishDate | 2023-08-01 |
| publisher | Instituto de Tecnologia do Paraná (Tecpar) |
| record_format | Article |
| series | Brazilian Archives of Biology and Technology |
| spelling | doaj.art-131248ec80ec404fbce3429df141841c2023-08-08T07:40:11ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1678-43242023-08-016610.1590/1678-4324-2023230096The Effect of Cefovecin Sodium in Shelter Dogs with Bacterial Lower Respiratory DiseaseSerkan İrfan Kösehttps://orcid.org/0000-0003-3189-6690Burçin Özerhttps://orcid.org/0000-0001-8965-9335Ramazan Gönencihttps://orcid.org/0000-0002-4043-2612Zafer Cantekinhttps://orcid.org/0000-0002-8837-0262Abstract This study evaluated the clinical and bacteriological efficacy of cefovecin sodium in shelter dogs with bacterial lower respiratory disease. All dogs (n = 32) with lower respiratory disease were divided into two treatment groups: the cefovecin (n = 16) and the ceftriaxone (n = 16) groups. On the first five days and the 8th day of treatment, and after treatment (15th day), the examination of all dogs was performed. Blood analysis and thoracic radiographic imaging were done. In bronchoalveolar lavage fluids, in the cefovecin group, Bordetella bronchiseptica (n=13), Staphylococcus spp. (n=9), Streptococcus spp. (n=7), Klebsiella pneumonia (n=1); in the ceftriaxone group; B. bronchiseptica (n=5), Escherichia coli (n=5), Pasteurella canis (n=4), Streptococcus spp. (n=3), Staphylococcus aureus (n=1), Pasteurella aerogenes (n=1) and Klebsiella oxytoca (n=1) were isolated and identified. Cefovecin and ceftriaxone sodium treatment protocols had anti-bacterial efficacies of 68.75% and 100%, respectively. In light of the study results, it is concluded that although cefovecin sodium looks to be an antibacterial drug that may be used to treat bacterial lower respiratory tract infections in shelter dogs due to its ease of use, cefovecin and other cephalosporins should not be used empirically as they may contribute to bacterial resistance.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100321&tlng=enBacterial lower respiratory infectioncefovecinclinical efficacyempirically treatmentshelter dog |
| spellingShingle | Serkan İrfan Köse Burçin Özer Ramazan Gönenci Zafer Cantekin The Effect of Cefovecin Sodium in Shelter Dogs with Bacterial Lower Respiratory Disease Brazilian Archives of Biology and Technology Bacterial lower respiratory infection cefovecin clinical efficacy empirically treatment shelter dog |
| title | The Effect of Cefovecin Sodium in Shelter Dogs with Bacterial Lower Respiratory Disease |
| title_full | The Effect of Cefovecin Sodium in Shelter Dogs with Bacterial Lower Respiratory Disease |
| title_fullStr | The Effect of Cefovecin Sodium in Shelter Dogs with Bacterial Lower Respiratory Disease |
| title_full_unstemmed | The Effect of Cefovecin Sodium in Shelter Dogs with Bacterial Lower Respiratory Disease |
| title_short | The Effect of Cefovecin Sodium in Shelter Dogs with Bacterial Lower Respiratory Disease |
| title_sort | effect of cefovecin sodium in shelter dogs with bacterial lower respiratory disease |
| topic | Bacterial lower respiratory infection cefovecin clinical efficacy empirically treatment shelter dog |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100321&tlng=en |
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