Unlocking the Power of Onion Peel Extracts: Antimicrobial and Anti-Inflammatory Effects Improve Wound Healing through Repressing Notch-1/NLRP3/Caspase-1 Signaling

Unlocking the Power of Onion Peel Extracts: Antimicrobial and Anti-Inflammatory Effects Improve Wound Healing through Repressing Notch-1/NLRP3/Caspase-1 Signaling

Onion peels are often discarded, representing an unlimited amount of food by-products; however, they are a valuable source of bioactive phenolics. Thus, we utilized UPLC-MS/MS to analyze the metabolomic profiles of red (RO) and yellow (YO) onion peel extracts. The cytotoxic (SRB assay), anti-inflamm...

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Bibliographic Details
Main Authors: Rafik Mounir, Walaa A. Alshareef, Eman A. El Gebaly, Alaadin E. El-Haddad, Abdallah M. Said Ahmed, Osama G. Mohamed, Eman T. Enan, Shaimaa Mosallam, Ashootosh Tripathi, Heba Mohammed Refat M. Selim, Sarah I. Bukhari, Rihaf Alfaraj, Ghada M. Ragab, Amira A. El-Gazar, Soad Z. El-Emam
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
dietary flavonoids
anthocyanins
quercetin
tissue regeneration
angiogenesis
VEGF
Online Access:https://www.mdpi.com/1424-8247/16/10/1379

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