Pain: a distributed brain information network?

Understanding how pain is processed in the brain has been an enduring puzzle, because there doesn't appear to be a single "pain cortex" that directly codes the subjective perception of pain. An emerging concept is that, instead, pain might emerge from the coordinated activity of an in...

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Main Authors: Hiroaki Mano, Ben Seymour
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4285395?pdf=render
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author Hiroaki Mano
Ben Seymour
author_facet Hiroaki Mano
Ben Seymour
author_sort Hiroaki Mano
collection DOAJ
description Understanding how pain is processed in the brain has been an enduring puzzle, because there doesn't appear to be a single "pain cortex" that directly codes the subjective perception of pain. An emerging concept is that, instead, pain might emerge from the coordinated activity of an integrated brain network. In support of this view, Woo and colleagues present evidence that distinct brain networks support the subjective changes in pain that result from nociceptive input and self-directed cognitive modulation. This evidence for the sensitivity of distinct neural subsystems to different aspects of pain opens up the way to more formal computational network theories of pain.
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spelling doaj.art-1316e4b595eb482c86baacb6e34af1e72022-12-21T22:01:15ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852015-01-01131e100203710.1371/journal.pbio.1002037Pain: a distributed brain information network?Hiroaki ManoBen SeymourUnderstanding how pain is processed in the brain has been an enduring puzzle, because there doesn't appear to be a single "pain cortex" that directly codes the subjective perception of pain. An emerging concept is that, instead, pain might emerge from the coordinated activity of an integrated brain network. In support of this view, Woo and colleagues present evidence that distinct brain networks support the subjective changes in pain that result from nociceptive input and self-directed cognitive modulation. This evidence for the sensitivity of distinct neural subsystems to different aspects of pain opens up the way to more formal computational network theories of pain.http://europepmc.org/articles/PMC4285395?pdf=render
spellingShingle Hiroaki Mano
Ben Seymour
Pain: a distributed brain information network?
PLoS Biology
title Pain: a distributed brain information network?
title_full Pain: a distributed brain information network?
title_fullStr Pain: a distributed brain information network?
title_full_unstemmed Pain: a distributed brain information network?
title_short Pain: a distributed brain information network?
title_sort pain a distributed brain information network
url http://europepmc.org/articles/PMC4285395?pdf=render
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