Interferon Regulatory Factor 3-Mediated Signaling Limits Middle-East Respiratory Syndrome (MERS) Coronavirus Propagation in Cells from an Insectivorous Bat

Interferon Regulatory Factor 3-Mediated Signaling Limits Middle-East Respiratory Syndrome (MERS) Coronavirus Propagation in Cells from an Insectivorous Bat

Insectivorous bats are speculated to be ancestral hosts of Middle-East respiratory syndrome (MERS) coronavirus (CoV). MERS-CoV causes disease in humans with thirty-five percent fatality, and has evolved proteins that counteract human antiviral responses. Since bats experimentally infected with MERS-...

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Bibliographic Details
Main Authors: Arinjay Banerjee, Darryl Falzarano, Noreen Rapin, Jocelyne Lew, Vikram Misra
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Viruses
Subjects:
bat
IRF3
MERS-CoV
interferon
Online Access:https://www.mdpi.com/1999-4915/11/2/152

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