Prognostic value of tumor mutation burden in patients with advanced gastric cancer receiving first-line chemotherapy

Prognostic value of tumor mutation burden in patients with advanced gastric cancer receiving first-line chemotherapy

BackgroundTumor mutation burden (TMB) is a promising biomarker positively associated with the benefit of immunotherapy and that might predict the outcome of chemotherapy. We described the prognostic value of TMB in advanced gastric cancer and explored the underlying mechanism.MethodsWe enrolled 155...

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Bibliographic Details
Main Authors:	Xiao-Peng Duan, Ke Liu, Xiao-Dong Jiao, Bao-Dong Qin, Bing Li, Xi He, Yan Ling, Ying Wu, Shi-Qi Chen, Yuan-Sheng Zang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Oncology
Subjects:	gastric cancer chemotherapy tumor mutation burden biomarker prognostic value mechanism
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.1007146/full

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