Effects of Ingestion of Different Amounts of Carbohydrate after Endurance Exercise on Circulating Cytokines and Markers of Neutrophil Activation
We aimed to examine the effects of ingestion of different amounts of carbohydrate (CHO) after endurance exercise on neutrophil count, circulating cytokine levels, and the markers of neutrophil activation and muscle damage. Nine participants completed three separate experimental trials consisting of...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-04-01
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| Series: | Antioxidants |
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| Online Access: | http://www.mdpi.com/2076-3921/7/4/51 |
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| author | Kumpei Tanisawa Katsuhiko Suzuki Sihui Ma Saki Kondo Susumu Okugawa Mitsuru Higuchi |
| author_facet | Kumpei Tanisawa Katsuhiko Suzuki Sihui Ma Saki Kondo Susumu Okugawa Mitsuru Higuchi |
| author_sort | Kumpei Tanisawa |
| collection | DOAJ |
| description | We aimed to examine the effects of ingestion of different amounts of carbohydrate (CHO) after endurance exercise on neutrophil count, circulating cytokine levels, and the markers of neutrophil activation and muscle damage. Nine participants completed three separate experimental trials consisting of 1 h of cycling exercise at 70% V · O2 max, followed by ingestion of 1.2 g CHO·kg body mass−1·h−1 (HCHO trial), 0.2 g CHO·kg body mass−1·h−1 (LCHO trial), or placebo (PLA trial) during the 2 h recovery phase in random order. Circulating glucose, insulin, and cytokine levels, blood cell counts, and the markers of neutrophil activation and muscle damage were measured. The concentrations of plasma glucose and serum insulin at 1 h after exercise were higher in the HCHO trial than in the LCHO and PLA trials. Although there were significant main effects of time on several variables, including neutrophil count, cytokine levels, and the markers of neutrophil activation and muscle damage, significant time × trial interactions were not observed for any variables. These results suggest that CHO ingestion after endurance exercise does not enhance exercise-induced increase in circulating neutrophil and cytokine levels and markers of neutrophil activation and muscle damage, regardless of the amount of CHO ingested. |
| first_indexed | 2024-03-12T07:14:55Z |
| format | Article |
| id | doaj.art-13245c039c504803843ad4fc3cc779e9 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-12T07:14:55Z |
| publishDate | 2018-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-13245c039c504803843ad4fc3cc779e92023-09-02T22:51:07ZengMDPI AGAntioxidants2076-39212018-04-01745110.3390/antiox7040051antiox7040051Effects of Ingestion of Different Amounts of Carbohydrate after Endurance Exercise on Circulating Cytokines and Markers of Neutrophil ActivationKumpei Tanisawa0Katsuhiko Suzuki1Sihui Ma2Saki Kondo3Susumu Okugawa4Mitsuru Higuchi5Department of Physical Activity Research, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo 162-8636, JapanFaculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanGraduate School of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanDepartment of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo 153-8902, JapanProducts Research & Development Laboratory, Asahi Soft Drinks Co., Ltd., Moriya 302-0106, JapanFaculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, JapanWe aimed to examine the effects of ingestion of different amounts of carbohydrate (CHO) after endurance exercise on neutrophil count, circulating cytokine levels, and the markers of neutrophil activation and muscle damage. Nine participants completed three separate experimental trials consisting of 1 h of cycling exercise at 70% V · O2 max, followed by ingestion of 1.2 g CHO·kg body mass−1·h−1 (HCHO trial), 0.2 g CHO·kg body mass−1·h−1 (LCHO trial), or placebo (PLA trial) during the 2 h recovery phase in random order. Circulating glucose, insulin, and cytokine levels, blood cell counts, and the markers of neutrophil activation and muscle damage were measured. The concentrations of plasma glucose and serum insulin at 1 h after exercise were higher in the HCHO trial than in the LCHO and PLA trials. Although there were significant main effects of time on several variables, including neutrophil count, cytokine levels, and the markers of neutrophil activation and muscle damage, significant time × trial interactions were not observed for any variables. These results suggest that CHO ingestion after endurance exercise does not enhance exercise-induced increase in circulating neutrophil and cytokine levels and markers of neutrophil activation and muscle damage, regardless of the amount of CHO ingested.http://www.mdpi.com/2076-3921/7/4/51exhaustionleukocyteinflammationmuscle damage |
| spellingShingle | Kumpei Tanisawa Katsuhiko Suzuki Sihui Ma Saki Kondo Susumu Okugawa Mitsuru Higuchi Effects of Ingestion of Different Amounts of Carbohydrate after Endurance Exercise on Circulating Cytokines and Markers of Neutrophil Activation Antioxidants exhaustion leukocyte inflammation muscle damage |
| title | Effects of Ingestion of Different Amounts of Carbohydrate after Endurance Exercise on Circulating Cytokines and Markers of Neutrophil Activation |
| title_full | Effects of Ingestion of Different Amounts of Carbohydrate after Endurance Exercise on Circulating Cytokines and Markers of Neutrophil Activation |
| title_fullStr | Effects of Ingestion of Different Amounts of Carbohydrate after Endurance Exercise on Circulating Cytokines and Markers of Neutrophil Activation |
| title_full_unstemmed | Effects of Ingestion of Different Amounts of Carbohydrate after Endurance Exercise on Circulating Cytokines and Markers of Neutrophil Activation |
| title_short | Effects of Ingestion of Different Amounts of Carbohydrate after Endurance Exercise on Circulating Cytokines and Markers of Neutrophil Activation |
| title_sort | effects of ingestion of different amounts of carbohydrate after endurance exercise on circulating cytokines and markers of neutrophil activation |
| topic | exhaustion leukocyte inflammation muscle damage |
| url | http://www.mdpi.com/2076-3921/7/4/51 |
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