Allelic variants of breast cancer susceptibility genes PALB2 and RECQL in the Latvian population

Allelic variants of breast cancer susceptibility genes PALB2 and RECQL in the Latvian population

Abstract Background Large-scale case control studies revealed a number of moderate risk - low frequency breast cancer alleles of the PALB2 and RECQL genes. Some of these were reported as founder variants of Central and Eastern Europe. Based on highly similar founder variant spectra of the BRCA1 in P...

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Main Authors: Philip Hilz, Reicela Heinrihsone, Lukas Alexander Pätzold, Qi Qi, Genadijs Trofimovics, Linda Gailite, Arvids Irmejs, Janis Gardovskis, Edvins Miklasevics, Zanda Daneberga
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Breast cancer
PALB2
RECQL
Moderate risk allele
Low frequency allele
Online Access:http://link.springer.com/article/10.1186/s13053-019-0116-6

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