Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid Nodules

Evaluate the values of SPECT,serum TSH and ultrasonography in the diagnoses of benign and malignant thyroid nodules. Retrospective analysis of SPECT ,serum TSH,and ultrasonography results of 89 patients with 141 thyroid nodules. And the examination results were compared with the post-operative path...

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Main Author: LIU Wei-ying1;GAO Qin-yi1;LI Ya-ming1;LI Yu-ge2
Format: Article
Language:zho
Published: Editorial Board of Journal of Isotopes 2014-02-01
Series:Journal of Isotopes
Subjects:
Online Access:http://www.tws.org.cn/CN/10.7538/tws.2014.27.01.0015
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author LIU Wei-ying1;GAO Qin-yi1;LI Ya-ming1;LI Yu-ge2
author_facet LIU Wei-ying1;GAO Qin-yi1;LI Ya-ming1;LI Yu-ge2
author_sort LIU Wei-ying1;GAO Qin-yi1;LI Ya-ming1;LI Yu-ge2
collection DOAJ
description Evaluate the values of SPECT,serum TSH and ultrasonography in the diagnoses of benign and malignant thyroid nodules. Retrospective analysis of SPECT ,serum TSH,and ultrasonography results of 89 patients with 141 thyroid nodules. And the examination results were compared with the post-operative pathological findings. It has statistical significance when the P-value of the significance test is smaller than 0.05. On SPECT, malignant rate of the “cold” nodules was 35.3%,and increased accompanied with the raising of serum TSH level (P<0.05) .The results image were corresponding to the serum TSH level.A high serum TSH level ofen appeared in the “cold” nodules and a low serum TSH level ofen appeared in the “hot” nodules (P<0.05).(2)The rate of malignant increased accompanied with the raising of serum TSH level (P<0.05) . The serum TSH level in patient with malignant cold nodule is higher than patient with benign cold nodule (P<0.05), and the best diagnosis TSH level is 1.695 mIU/L with sensitivity and specificity 83.8% and 77.3%, respectively. The best diagnosis TSH level in patient with solid cold nodule is 1.675 mIU/L with sensitivity and specificity 83.3% and 100%,respectively.Therefor,TSH level has no diagnositic significance in patient with hot,warm,or cool nodules (P>0.05) .The combination of thyroid imaging may help to evaluate the functions and the form of thyroid nodules, serum TSH and ultrasonography so that it plays an important role in the differentiation of benign and malignant thyroid nodules.
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spelling doaj.art-13282c3b917743849327f8cd4d1e527e2022-12-22T01:43:02ZzhoEditorial Board of Journal of IsotopesJournal of Isotopes1000-75121000-75122014-02-01271152110.7538/tws.2014.27.01.0015 Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid NodulesLIU Wei-ying1;GAO Qin-yi1;LI Ya-ming1;LI Yu-ge2Evaluate the values of SPECT,serum TSH and ultrasonography in the diagnoses of benign and malignant thyroid nodules. Retrospective analysis of SPECT ,serum TSH,and ultrasonography results of 89 patients with 141 thyroid nodules. And the examination results were compared with the post-operative pathological findings. It has statistical significance when the P-value of the significance test is smaller than 0.05. On SPECT, malignant rate of the “cold” nodules was 35.3%,and increased accompanied with the raising of serum TSH level (P<0.05) .The results image were corresponding to the serum TSH level.A high serum TSH level ofen appeared in the “cold” nodules and a low serum TSH level ofen appeared in the “hot” nodules (P<0.05).(2)The rate of malignant increased accompanied with the raising of serum TSH level (P<0.05) . The serum TSH level in patient with malignant cold nodule is higher than patient with benign cold nodule (P<0.05), and the best diagnosis TSH level is 1.695 mIU/L with sensitivity and specificity 83.8% and 77.3%, respectively. The best diagnosis TSH level in patient with solid cold nodule is 1.675 mIU/L with sensitivity and specificity 83.3% and 100%,respectively.Therefor,TSH level has no diagnositic significance in patient with hot,warm,or cool nodules (P>0.05) .The combination of thyroid imaging may help to evaluate the functions and the form of thyroid nodules, serum TSH and ultrasonography so that it plays an important role in the differentiation of benign and malignant thyroid nodules.http://www.tws.org.cn/CN/10.7538/tws.2014.27.01.0015 SPECT TSH ultrasonography thyroid nodules malignant
spellingShingle LIU Wei-ying1;GAO Qin-yi1;LI Ya-ming1;LI Yu-ge2
Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid Nodules
Journal of Isotopes
SPECT TSH ultrasonography thyroid nodules malignant
title Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid Nodules
title_full Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid Nodules
title_fullStr Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid Nodules
title_full_unstemmed Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid Nodules
title_short Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid Nodules
title_sort values of radionuclide imaging serum tsh and ultrasonography in the diagnoses of thyroid nodules
topic SPECT TSH ultrasonography thyroid nodules malignant
url http://www.tws.org.cn/CN/10.7538/tws.2014.27.01.0015
work_keys_str_mv AT liuweiying1gaoqinyi1liyaming1liyuge2 valuesofradionuclideimagingserumtshandultrasonographyinthediagnosesofthyroidnodules