Effect of betamethasone on neonatal respiratory failure in late preterm pregnancies
Background and Objective: Respiratory failure is one of the most important respiratory problems in premature infants. Several studies have shown the efficacy of corticosteroids in gestational age less than 34 weeks. This study was done to determine the effect of prenatal betamethasone injection duri...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | fas |
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Golestan University of Medical Sciences
2015-12-01
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| Series: | مجله دانشگاه علوم پزشکی گرگان |
| Subjects: | |
| Online Access: | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-860&slc_lang=en&sid=1 |
| _version_ | 1824018715280146432 |
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| author | Haji Seid Javadi E Movahed F Baricany A Jafari M |
| author_facet | Haji Seid Javadi E Movahed F Baricany A Jafari M |
| author_sort | Haji Seid Javadi E |
| collection | DOAJ |
| description | Background and Objective: Respiratory failure is one of the most important respiratory problems in premature infants. Several studies have shown the efficacy of corticosteroids in gestational age less than 34 weeks. This study was done to determine the effect of prenatal betamethasone injection during 34 to 36 weeks of pregnancy on the prevention of newborn respiratory failure. Methods: This clinical trial study was conducted on 140 women with risk of preterm labor at 34 to 36 weeks of gestational age. Women in interventional group were received betamethasone 12 mg IM (2 doses, 12 hours apart). Women in control group were received the same volume of normal saline. Sex and birth weight, respiratory distress syndrome, requiring hospitalization in neonatal intensive care units and require respiratory support were recorded for each newborn. Results: No significant difference was seen in sex and weight of newborns between two groups. The precent of newborns with respiratory distress syndrome in the intervention and control groups was 12.5% and 22%, respectively. This difference was not significant. No significant difference was seen in the need to respiratory support, hospitalized in the NICU between intervention and control groups. Conclusion: Adminestration of betamethasone in 36-34 weeks of pregnancy has no effect on the prevention of respiratory failure in preterm infants. |
| first_indexed | 2024-12-19T01:09:46Z |
| format | Article |
| id | doaj.art-132a566f9ba14791b77dab6eb4899492 |
| institution | Directory Open Access Journal |
| issn | 1562-4765 2008-4080 |
| language | fas |
| last_indexed | 2024-12-19T01:09:46Z |
| publishDate | 2015-12-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشگاه علوم پزشکی گرگان |
| spelling | doaj.art-132a566f9ba14791b77dab6eb48994922022-12-21T20:43:04ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40802015-12-011741620Effect of betamethasone on neonatal respiratory failure in late preterm pregnanciesHaji Seid Javadi E0Movahed F1Baricany A2Jafari M3 Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran Associate Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran Associate Professor, Department of Community medicine, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran Resident in Obstetrics and Gynecology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran Background and Objective: Respiratory failure is one of the most important respiratory problems in premature infants. Several studies have shown the efficacy of corticosteroids in gestational age less than 34 weeks. This study was done to determine the effect of prenatal betamethasone injection during 34 to 36 weeks of pregnancy on the prevention of newborn respiratory failure. Methods: This clinical trial study was conducted on 140 women with risk of preterm labor at 34 to 36 weeks of gestational age. Women in interventional group were received betamethasone 12 mg IM (2 doses, 12 hours apart). Women in control group were received the same volume of normal saline. Sex and birth weight, respiratory distress syndrome, requiring hospitalization in neonatal intensive care units and require respiratory support were recorded for each newborn. Results: No significant difference was seen in sex and weight of newborns between two groups. The precent of newborns with respiratory distress syndrome in the intervention and control groups was 12.5% and 22%, respectively. This difference was not significant. No significant difference was seen in the need to respiratory support, hospitalized in the NICU between intervention and control groups. Conclusion: Adminestration of betamethasone in 36-34 weeks of pregnancy has no effect on the prevention of respiratory failure in preterm infants.http://goums.ac.ir/journal/browse.php?a_code=A-10-1-860&slc_lang=en&sid=1Neonatal respiratory distress syndromeBetamethasonePreterm labor |
| spellingShingle | Haji Seid Javadi E Movahed F Baricany A Jafari M Effect of betamethasone on neonatal respiratory failure in late preterm pregnancies مجله دانشگاه علوم پزشکی گرگان Neonatal respiratory distress syndrome Betamethasone Preterm labor |
| title | Effect of betamethasone on neonatal respiratory failure in late preterm pregnancies |
| title_full | Effect of betamethasone on neonatal respiratory failure in late preterm pregnancies |
| title_fullStr | Effect of betamethasone on neonatal respiratory failure in late preterm pregnancies |
| title_full_unstemmed | Effect of betamethasone on neonatal respiratory failure in late preterm pregnancies |
| title_short | Effect of betamethasone on neonatal respiratory failure in late preterm pregnancies |
| title_sort | effect of betamethasone on neonatal respiratory failure in late preterm pregnancies |
| topic | Neonatal respiratory distress syndrome Betamethasone Preterm labor |
| url | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-860&slc_lang=en&sid=1 |
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