Establishment of a risk prediction model for postoperative constipation in patients with oral and maxillofacial malignant tumors
Objective To understand the incidence and influencing factors of postoperative constipation in patients with malignant tumors who undergo oral and maxillofacial surgery and construct a constipation risk prediction model to provide a reference for the prevention and treatment of postoperative constip...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
2022-08-01
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| Series: | 口腔疾病防治 |
| Subjects: | |
| Online Access: | http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2022.08.005 |
| _version_ | 1828794079972950016 |
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| author | ZHU Huixuan HE Xingfang HUANG Qiuyu LIU Manfeng LIN Yantong |
| author_facet | ZHU Huixuan HE Xingfang HUANG Qiuyu LIU Manfeng LIN Yantong |
| author_sort | ZHU Huixuan |
| collection | DOAJ |
| description | Objective To understand the incidence and influencing factors of postoperative constipation in patients with malignant tumors who undergo oral and maxillofacial surgery and construct a constipation risk prediction model to provide a reference for the prevention and treatment of postoperative constipation. Methods The data of 191 patients who underwent oral and maxillofacial malignant tumor surgery at the Affiliated Stomatological Hospital of Sun Yat sen University from June 2019 to June 2020 were analyzed retrospectively. The independent influencing factors were selected via univariate analysis and logistic multivariate regression analysis, a risk prediction nomogram was established, and the prediction model was evaluated by the area under the ROC curve. Both internal and external use the C index to verify the accuracy of the model. Results Among 191 patients, 52 (27.23%) had postoperative constipation. Univariate analysis showed that a preoperative secret history of defecation, total energy intake, tracheotomy, smoking, drinking, operation duration, bleeding volume, bed time, eating homogenate diet, sex, surgical repair method, use of probiotics, T-stage of cancer and food intake may be the influencing factors of postoperative constipation in patients with oral and maxillofacial malignant tumors (P<0.05). Multivariate analysis showed that repair method, bed time and sex were independent risk factors for postoperative constipation in patients with oral and maxillofacial malignant tumors (P<0.05). The repair method was a fibular myocutaneous flap with a long bed time, and male patients were prone to constipation after surgery. The c-index values in the training group and the verification group were 0.882 and 0.953, respectively. The area under the ROC curve of the training group was 0.909 (95%CI: 0.850-0.968), and the area under the ROC curve of the verification group was 0.893 (95%CI: 0.787-0.999). The nomogram showed good discrimination ability. Conclusion The repair method, bed time and sex are independent risk factors for postoperative constipation in patients with oral and maxillofacial malignant tumors. The risk prediction model has good discrimination ability. |
| first_indexed | 2024-12-12T03:39:00Z |
| format | Article |
| id | doaj.art-132fcdd18f3949aaa84fddd96a41db8a |
| institution | Directory Open Access Journal |
| issn | 2096-1456 |
| language | zho |
| last_indexed | 2024-12-12T03:39:00Z |
| publishDate | 2022-08-01 |
| publisher | Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases |
| record_format | Article |
| series | 口腔疾病防治 |
| spelling | doaj.art-132fcdd18f3949aaa84fddd96a41db8a2022-12-22T00:39:43ZzhoEditorial Department of Journal of Prevention and Treatment for Stomatological Diseases口腔疾病防治2096-14562022-08-0130856457010.12016/j.issn.2096-1456.2022.08.005Establishment of a risk prediction model for postoperative constipation in patients with oral and maxillofacial malignant tumorsZHU Huixuan0HE Xingfang1HUANG Qiuyu2LIU Manfeng3 LIN Yantong4Stomatological Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of StomatologyStomatological Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of StomatologyStomatological Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of StomatologyStomatological Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of StomatologyStomatological Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of StomatologyObjective To understand the incidence and influencing factors of postoperative constipation in patients with malignant tumors who undergo oral and maxillofacial surgery and construct a constipation risk prediction model to provide a reference for the prevention and treatment of postoperative constipation. Methods The data of 191 patients who underwent oral and maxillofacial malignant tumor surgery at the Affiliated Stomatological Hospital of Sun Yat sen University from June 2019 to June 2020 were analyzed retrospectively. The independent influencing factors were selected via univariate analysis and logistic multivariate regression analysis, a risk prediction nomogram was established, and the prediction model was evaluated by the area under the ROC curve. Both internal and external use the C index to verify the accuracy of the model. Results Among 191 patients, 52 (27.23%) had postoperative constipation. Univariate analysis showed that a preoperative secret history of defecation, total energy intake, tracheotomy, smoking, drinking, operation duration, bleeding volume, bed time, eating homogenate diet, sex, surgical repair method, use of probiotics, T-stage of cancer and food intake may be the influencing factors of postoperative constipation in patients with oral and maxillofacial malignant tumors (P<0.05). Multivariate analysis showed that repair method, bed time and sex were independent risk factors for postoperative constipation in patients with oral and maxillofacial malignant tumors (P<0.05). The repair method was a fibular myocutaneous flap with a long bed time, and male patients were prone to constipation after surgery. The c-index values in the training group and the verification group were 0.882 and 0.953, respectively. The area under the ROC curve of the training group was 0.909 (95%CI: 0.850-0.968), and the area under the ROC curve of the verification group was 0.893 (95%CI: 0.787-0.999). The nomogram showed good discrimination ability. Conclusion The repair method, bed time and sex are independent risk factors for postoperative constipation in patients with oral and maxillofacial malignant tumors. The risk prediction model has good discrimination ability.http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2022.08.005constipation，postoperative，oral and maxillofacial，surgical，malignant tumors，risk prediction，model，risk factor， |
| spellingShingle | ZHU Huixuan HE Xingfang HUANG Qiuyu LIU Manfeng LIN Yantong Establishment of a risk prediction model for postoperative constipation in patients with oral and maxillofacial malignant tumors 口腔疾病防治 constipation， postoperative， oral and maxillofacial， surgical， malignant tumors， risk prediction， model， risk factor， |
| title | Establishment of a risk prediction model for postoperative constipation in patients with oral and maxillofacial malignant tumors |
| title_full | Establishment of a risk prediction model for postoperative constipation in patients with oral and maxillofacial malignant tumors |
| title_fullStr | Establishment of a risk prediction model for postoperative constipation in patients with oral and maxillofacial malignant tumors |
| title_full_unstemmed | Establishment of a risk prediction model for postoperative constipation in patients with oral and maxillofacial malignant tumors |
| title_short | Establishment of a risk prediction model for postoperative constipation in patients with oral and maxillofacial malignant tumors |
| title_sort | establishment of a risk prediction model for postoperative constipation in patients with oral and maxillofacial malignant tumors |
| topic | constipation， postoperative， oral and maxillofacial， surgical， malignant tumors， risk prediction， model， risk factor， |
| url | http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2022.08.005 |
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