Preclinical safety of a bionic tiger bone capsule in Sprague–Dawley rats and beagle dogs

Preclinical safety of a bionic tiger bone capsule in Sprague–Dawley rats and beagle dogs

Abstract Background Jintiange capsule is composed of bionic tiger bone powder and has similar ingredients to natural tiger bone. Objective To characterize the subacute toxicities of Jintiange capsule in rats and beagle dogs for preclinical safety assessment. Methods Suspensions of Jintiange capsule...

Full description

Bibliographic Details
Main Authors:	Shu‐Fang Wan, Quan‐Jun Wang, Yong‐Biao Guan
Format:	Article
Language:	English
Published:	Wiley 2022-11-01
Series:	Veterinary Medicine and Science
Subjects:	beagles bionic tiger bone capsule Jintiange rats subacute toxicity
Online Access:	https://doi.org/10.1002/vms3.913

Similar Items

Effect of Artificial Tiger Bone Powder (Jintiange Capsule®) on Vertebral Height Ratio, Cobb's Angle, Bone Mineral Density, and Visual Analog Score
by: Long‐jun Shu, et al.
Published: (2022-02-01)

Effect of Jintiange capsule on acute bone atrophy resulting from wrist fractures: A randomized controlled trial
by: Li-You Wei, et al.
Published: (2020-01-01)

Jintiange Capsules Ameliorate Osteoarthritis by Modulating Subchondral Bone Remodeling and Protecting Cartilage Against Degradation
by: Chenyang Zhuang, et al.
Published: (2021-11-01)

Jintiange combined with alfacalcidol improves muscle strength and balance in primary osteoporosis: A randomized, double-blind, double-dummy, positive-controlled, multicenter clinical trial
by: Hanting Liang, et al.
Published: (2022-07-01)

Pharmacokinetics of propafenone hydrochloride sustained-release capsules in male beagle dogs
by: Liping Pan, et al.
Published: (2015-01-01)

Pharmacokinetic study of the main components of Tanreqing capsules and Tanreqing injections in beagles by liquid chromatography–tandem mass spectrometry
by: Lili Cui, et al.
Published: (2022-12-01)

Safety Assessment of Acer tegmentosum Maxim. Water Extract: General Toxicity Studies in Sprague–Dawley Rats and Beagle Dogs With Re-evaluation of Genotoxic Potentials
by: Jin-Sung Park, et al.
Published: (2021-08-01)

Subacute Toxicity of Brown Truffle (Terfezia claveryi) on Sprague-Dawley Rats
by: Hiewa O. Dyary
Published: (2020-12-01)

Sub-acute Toxicity Study of Tiger Milk Mushroom Lignosus tigris Chon S. Tan Cultivar E Sclerotium in Sprague Dawley Rats
by: Shin Yee Fung, et al.
Published: (2016-08-01)

Efficacy of the Chinese herbal medicine Jintiange capsules in the postoperative treatment of osteoporotic vertebral compression fractures: a systematic review and meta-analysis
by: Yongsheng Fu, et al.
Published: (2023-12-01)

Evaluation of Marbofloxacin in Beagle Dogs After Oral Dosing: Preclinical Safety Evaluation and Comparative Pharmacokinetics of Two Different Tablets
by: Zhixin Lei, et al.
Published: (2018-04-01)

Lipidomic changes in the liver of beagle dogs associated with Toxocara canis infection
by: Hao-Yu Li, et al.
Published: (2022-09-01)

Establishment of a spontaneous ventilation anesthesia model for beagle dogs
by: Yuan Zeng, et al.
Published: (2024-06-01)

Corrigendum: Evaluation of Marbofloxacin in Beagle Dogs After Oral Dosing: Preclinical Safety Evaluation and Comparative Pharmacokinetics of Two Different Tablets
by: Zhixin Lei, et al.
Published: (2018-11-01)

Acute and subacute oral toxicity assessment of Gancao Xiexin decoction in Sprague-Dawley rats
by: Li Ru, et al.
Published: (2023-01-01)

Pharmacokinetic comparisons of S-oxiracetam and R-oxiracetam in beagle dogs
by: Wang Wusan, et al.
Published: (2016-06-01)

Clinical Phenotype of Musladin‐Lueke Syndrome in 2 Beagles
by: R.A. Packer, et al.
Published: (2017-03-01)

Selected biomarkers of oxidative stress in healthy Beagle dogs: A preliminary study
by: Mathilde Porato, et al.
Published: (2023-03-01)

Tiger, tiger /
by: Banks, Lynne Reid, 1929-
Published: (2004)

Bionics for the evil genius /
by: 291198 Braga, Newton C.
Published: (2006)

Evaluation of pharmacokinetics underlies the collaborated usage of lamivudine and oxymatrine in beagle dogs
by: Zhenbao Li, et al.
Published: (2016-10-01)

Pharmacokinetics and metabolism of cyadox and its main metabolites in beagle dogs following oral, intramuscular and intravenous administration
by: Adeel Sattar, et al.
Published: (2016-08-01)

TIGERS /
by: Seidensticker, John, author
Published: (1996)

Determination of knee cartilage volume and surface area in beagle dogs: a pilot study
by: Aad Dhollander, et al.
Published: (2017-11-01)

Preparation, characterization, and pharmacokinetics of rivaroxaban cocrystals with enhanced in vitro and in vivo properties in beagle dogs
by: Yuanyuan Meng, et al.
Published: (2022-12-01)

Comparison of fecal microbiota of SPF and non-SPF Beagle dogs
by: Cuilian Yu, et al.
Published: (2023-02-01)

Serum metabolomic alterations in Beagle dogs experimentally infected with Toxocara canis
by: Wen-Bin Zheng, et al.
Published: (2019-09-01)

Effects of Sweet Bee Venom on cardiovascular system in the conscious telemetered Beagle Dogs
by: Lim Chung-San, et al.
Published: (2010-09-01)

The Beagle conflict
by: Peter van Aert
Published: (2016-05-01)

The tigers of Trengganu /
by: 427298 Locke, A.
Published: (1993)

Lung Lipidomic Alterations in Beagle Dogs Infected with <i>Toxocara canis</i>
by: Hao-Yu Li, et al.
Published: (2022-11-01)

Toxocara canis Differentially Affects Hepatic MicroRNA Expression in Beagle Dogs at Different Stages of Infection
by: Yang Zou, et al.
Published: (2020-11-01)

Tigers : the secret life/
by: 210507 Thapar, Valmik
Published: (1989)

Study of single dose toxic test of Sweet Bee Venom in Beagle Dogs
by: Hye-Chul, Yoon, et al.
Published: (2010-12-01)

Development of an UPLC-MS/MS Method for the Quantitative Analysis of Upadacitinib in Beagle Dog Plasma and Pharmacokinetics Study
by: Wang MJ, et al.
Published: (2021-10-01)

Subacute Toxicity Study of Nicotinamide Mononucleotide via Oral Administration
by: Yingnan You, et al.
Published: (2020-12-01)

Primary angle-closure glaucoma with goniodysgenesis in a Beagle dog
by: Shin Ae Park, et al.
Published: (2019-03-01)

Differential miRNA expression profiles in the bone marrow of Beagle dogs at different stages of Toxocara canis infection
by: Jin Gao, et al.
Published: (2022-12-01)

Mannoheptulose has differential effects on fasting and postprandial energy expenditure and respiratory quotient in adult Beagle dogs fed diets of different macronutrient contents
by: Leslie L. McKnight, et al.
Published: (2014-01-01)

The Pharmacokinetic Effect of Itraconazole and Voriconazole on Ripretinib in Beagle Dogs by UPLC-MS/MS Technique
by: Wang H, et al.
Published: (2021-11-01)