Pemphigus vulgaris – A report of three cases and review of literature
Pemphigus vulgaris (PV) is an autoimmune, potentially life-threatening disease causing blisters and erosions of the skin and mucous membranes associated with intraepithelial acantholysis. The underlying mechanism responsible for causing intraepithelial lesions is the binding of immunoglobulin G auto...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2018;volume=7;issue=5;spage=1109;epage=1112;aulast=Banerjee |
| _version_ | 1818328055454629888 |
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| author | Ishita Banerjee Biyas Bhowmik Anirban Maji Rupam Sinha |
| author_facet | Ishita Banerjee Biyas Bhowmik Anirban Maji Rupam Sinha |
| author_sort | Ishita Banerjee |
| collection | DOAJ |
| description | Pemphigus vulgaris (PV) is an autoimmune, potentially life-threatening disease causing blisters and erosions of the skin and mucous membranes associated with intraepithelial acantholysis. The underlying mechanism responsible for causing intraepithelial lesions is the binding of immunoglobulin G autoantibodies to desmoglein 3, a transmembrane glycoprotein adhesion molecule present on desmosomes. Histological features comprise intraepithelial cleft and Tzanck cells. Corticosteroids remain the mainstay of the treatment plan. In this article, we have discussed about the diagnosis of three patients suffering from PV, the treatment rendered, and the outcome of the same. |
| first_indexed | 2024-12-13T12:26:05Z |
| format | Article |
| id | doaj.art-133679daf63441e696a182477f3e721a |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-12-13T12:26:05Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-133679daf63441e696a182477f3e721a2022-12-21T23:46:17ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632018-01-01751109111210.4103/jfmpc.jfmpc_133_18Pemphigus vulgaris – A report of three cases and review of literatureIshita BanerjeeBiyas BhowmikAnirban MajiRupam SinhaPemphigus vulgaris (PV) is an autoimmune, potentially life-threatening disease causing blisters and erosions of the skin and mucous membranes associated with intraepithelial acantholysis. The underlying mechanism responsible for causing intraepithelial lesions is the binding of immunoglobulin G autoantibodies to desmoglein 3, a transmembrane glycoprotein adhesion molecule present on desmosomes. Histological features comprise intraepithelial cleft and Tzanck cells. Corticosteroids remain the mainstay of the treatment plan. In this article, we have discussed about the diagnosis of three patients suffering from PV, the treatment rendered, and the outcome of the same.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2018;volume=7;issue=5;spage=1109;epage=1112;aulast=BanerjeeCorticosteroidsNikolsky's signTzanck cellsvesicles |
| spellingShingle | Ishita Banerjee Biyas Bhowmik Anirban Maji Rupam Sinha Pemphigus vulgaris – A report of three cases and review of literature Journal of Family Medicine and Primary Care Corticosteroids Nikolsky's sign Tzanck cells vesicles |
| title | Pemphigus vulgaris – A report of three cases and review of literature |
| title_full | Pemphigus vulgaris – A report of three cases and review of literature |
| title_fullStr | Pemphigus vulgaris – A report of three cases and review of literature |
| title_full_unstemmed | Pemphigus vulgaris – A report of three cases and review of literature |
| title_short | Pemphigus vulgaris – A report of three cases and review of literature |
| title_sort | pemphigus vulgaris a report of three cases and review of literature |
| topic | Corticosteroids Nikolsky's sign Tzanck cells vesicles |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2018;volume=7;issue=5;spage=1109;epage=1112;aulast=Banerjee |
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