The use of fibrin sealant (Tisseel) in laparoscopic excision of ovarian endometrioma

Objective: To evaluate the use of Tisseel, a 2-component fibrin sealant agent for the control of minor bleeding and repair of the ovarian defect at the end of laparoscopic cystectomy (LC) of endometriomas. Materials and methods: From January 2011 to December 2015, an observational study of all patie...

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Main Authors: Yu-Cheng Liu, Yi-Chieh Li, Hsin-Hong Kuo, Chin-Jung Wang, Kai-Yun Wu
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455917300840
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author Yu-Cheng Liu
Yi-Chieh Li
Hsin-Hong Kuo
Chin-Jung Wang
Kai-Yun Wu
author_facet Yu-Cheng Liu
Yi-Chieh Li
Hsin-Hong Kuo
Chin-Jung Wang
Kai-Yun Wu
author_sort Yu-Cheng Liu
collection DOAJ
description Objective: To evaluate the use of Tisseel, a 2-component fibrin sealant agent for the control of minor bleeding and repair of the ovarian defect at the end of laparoscopic cystectomy (LC) of endometriomas. Materials and methods: From January 2011 to December 2015, an observational study of all patients who underwent LC of endometrioma using Tisseel (group A) was performed. The demographic and operative data, including age, body mass index, operative indications, operative time, estimated blood loss, complications, and postoperative hospital stay duration were recorded. A contemporary cohort of patients, who underwent LC of endometrioma without Tisseel (group B) was also retrospectively compared. Results: A total of 274 patients were recruited in this study (53 LCs with Tisseel and 221 LCs without Tisseel, respectively). Complete hemostasis was achieved in all patients. The mean size of main mass was significantly larger in the group A than in the group B (7.8 ± 2.4 cm vs. 7.0 ± 2.3 cm, p = 0.033) but the mean operating time, operative blood loss, febrile morbidity, and length of hospitalization were not significantly different between the two groups. Conclusion: This preliminary series demonstrated the use of Tisseel in LC of endometriomas without any bipolar coagulation and/or suturing of ovarian tissue is clinically safe and feasible.
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spelling doaj.art-133fd1eeb3af4936894c9b36ecf61c692022-12-21T23:55:45ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592017-06-0156334234510.1016/j.tjog.2017.04.014The use of fibrin sealant (Tisseel) in laparoscopic excision of ovarian endometriomaYu-Cheng LiuYi-Chieh LiHsin-Hong KuoChin-Jung WangKai-Yun WuObjective: To evaluate the use of Tisseel, a 2-component fibrin sealant agent for the control of minor bleeding and repair of the ovarian defect at the end of laparoscopic cystectomy (LC) of endometriomas. Materials and methods: From January 2011 to December 2015, an observational study of all patients who underwent LC of endometrioma using Tisseel (group A) was performed. The demographic and operative data, including age, body mass index, operative indications, operative time, estimated blood loss, complications, and postoperative hospital stay duration were recorded. A contemporary cohort of patients, who underwent LC of endometrioma without Tisseel (group B) was also retrospectively compared. Results: A total of 274 patients were recruited in this study (53 LCs with Tisseel and 221 LCs without Tisseel, respectively). Complete hemostasis was achieved in all patients. The mean size of main mass was significantly larger in the group A than in the group B (7.8 ± 2.4 cm vs. 7.0 ± 2.3 cm, p = 0.033) but the mean operating time, operative blood loss, febrile morbidity, and length of hospitalization were not significantly different between the two groups. Conclusion: This preliminary series demonstrated the use of Tisseel in LC of endometriomas without any bipolar coagulation and/or suturing of ovarian tissue is clinically safe and feasible.http://www.sciencedirect.com/science/article/pii/S1028455917300840EndometriomaFibrin sealantLaparoscopyOvaryTisseel
spellingShingle Yu-Cheng Liu
Yi-Chieh Li
Hsin-Hong Kuo
Chin-Jung Wang
Kai-Yun Wu
The use of fibrin sealant (Tisseel) in laparoscopic excision of ovarian endometrioma
Taiwanese Journal of Obstetrics & Gynecology
Endometrioma
Fibrin sealant
Laparoscopy
Ovary
Tisseel
title The use of fibrin sealant (Tisseel) in laparoscopic excision of ovarian endometrioma
title_full The use of fibrin sealant (Tisseel) in laparoscopic excision of ovarian endometrioma
title_fullStr The use of fibrin sealant (Tisseel) in laparoscopic excision of ovarian endometrioma
title_full_unstemmed The use of fibrin sealant (Tisseel) in laparoscopic excision of ovarian endometrioma
title_short The use of fibrin sealant (Tisseel) in laparoscopic excision of ovarian endometrioma
title_sort use of fibrin sealant tisseel in laparoscopic excision of ovarian endometrioma
topic Endometrioma
Fibrin sealant
Laparoscopy
Ovary
Tisseel
url http://www.sciencedirect.com/science/article/pii/S1028455917300840
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