A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans

A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans

Abstract XRN2 is an evolutionarily conserved 5’-to-3’ exoribonuclease, which degrades or trims various types of RNA in the nucleus. Although XRN-2 is essential for embryogenesis, larval development and reproduction in Caenorhabditis elegans, relevant molecular pathways remain unidentified. Here we c...

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Bibliographic Details
Main Authors:	Ilkin Aygün, Alicja Rzepczak, Takashi S. Miki
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Genética 2023-05-01
Series:	Genetics and Molecular Biology
Subjects:	XRN2 C34C12.2 glycerol regulation mutagenesis screen germline development
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572023000400701&lng=en&tlng=en

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