The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia

The global evolution of the SARS-CoV-2 virus is known to all. The diagnosis of SARS-CoV-2 pneumonia is expected to worsen, and mortality will be higher when combined with myocardial injury (MI). The combination of novel coronavirus infections in patients with MI can cause confusion in diagnosis and...

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Main Authors: Mohammed Ahmed Akkaif, Ahmad Naoras Bitar, Laith A. I. K. Al-Kaif, Nur Aizati Athirah Daud, Abubakar Sha’aban, Dzul Azri Mohamed Noor, Fatimatuzzahra’ Abd Aziz, Arturo Cesaro, Muhamad Ali SK Abdul Kader, Mohamed Jahangir Abdul Wahab, Chee Sin Khaw, Baharudin Ibrahim
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/9/9/307
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author Mohammed Ahmed Akkaif
Ahmad Naoras Bitar
Laith A. I. K. Al-Kaif
Nur Aizati Athirah Daud
Abubakar Sha’aban
Dzul Azri Mohamed Noor
Fatimatuzzahra’ Abd Aziz
Arturo Cesaro
Muhamad Ali SK Abdul Kader
Mohamed Jahangir Abdul Wahab
Chee Sin Khaw
Baharudin Ibrahim
author_facet Mohammed Ahmed Akkaif
Ahmad Naoras Bitar
Laith A. I. K. Al-Kaif
Nur Aizati Athirah Daud
Abubakar Sha’aban
Dzul Azri Mohamed Noor
Fatimatuzzahra’ Abd Aziz
Arturo Cesaro
Muhamad Ali SK Abdul Kader
Mohamed Jahangir Abdul Wahab
Chee Sin Khaw
Baharudin Ibrahim
author_sort Mohammed Ahmed Akkaif
collection DOAJ
description The global evolution of the SARS-CoV-2 virus is known to all. The diagnosis of SARS-CoV-2 pneumonia is expected to worsen, and mortality will be higher when combined with myocardial injury (MI). The combination of novel coronavirus infections in patients with MI can cause confusion in diagnosis and assessment, with each condition exacerbating the other, and increasing the complexity and difficulty of treatment. It would be a formidable challenge for clinical practice to deal with this situation. Therefore, this review aims to gather literature on the progress in managing MI related to SARS-CoV-2 pneumonia. This article reviews the definition, pathogenesis, clinical evaluation, management, and treatment plan for MI related to SARS-CoV-2 pneumonia based on the most recent literature, diagnosis, and treatment trial reports. Many studies have shown that early diagnosis and implementation of targeted treatment measures according to the different stages of disease can reduce the mortality rate among patients with MI related to SARS-CoV-2 pneumonia. The reviewed studies show that multiple strategies have been adopted for the management of MI related to COVID-19. Clinicians should closely monitor SARS-CoV-2 pneumonia patients with MI, as their condition can rapidly deteriorate and progress to heart failure, acute myocardial infarction, and/or cardiogenic shock. In addition, appropriate measures need to be implemented in the diagnosis and treatment to provide reasonable care to the patient.
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spelling doaj.art-1343918596404b1d86d2bdacd4abf6f82023-11-23T16:57:27ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252022-09-019930710.3390/jcdd9090307The Management of Myocardial Injury Related to SARS-CoV-2 PneumoniaMohammed Ahmed Akkaif0Ahmad Naoras Bitar1Laith A. I. K. Al-Kaif2Nur Aizati Athirah Daud3Abubakar Sha’aban4Dzul Azri Mohamed Noor5Fatimatuzzahra’ Abd Aziz6Arturo Cesaro7Muhamad Ali SK Abdul Kader8Mohamed Jahangir Abdul Wahab9Chee Sin Khaw10Baharudin Ibrahim11School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, MalaysiaDepartment of Clinical Pharmacy, Michel Sayegh College of Pharmacy, Aqaba University of Technology, South of Aqaba, South Beach Road, Opposite Aqaba Development Corporation Stores, Aqaba 910122, JordanDepartment of Medical Laboratory Techniques, Al Mustaqbal University College, Hillah 51001, Babylon, IraqSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, MalaysiaSchool of Medicine, Cardiff University, Heath Park, Cardiff CF14 4YS, UKSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, MalaysiaSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, MalaysiaDepartment of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, 80131 Naples, ItalyDepartment of Cardiology, Penang General Hospital, George Town 10990, MalaysiaDepartment of Cardiology, Penang General Hospital, George Town 10990, MalaysiaDepartment of Cardiology, Penang General Hospital, George Town 10990, MalaysiaFaculty of Pharmacy, University of Malaya, Kuala Lumpur 50603, MalaysiaThe global evolution of the SARS-CoV-2 virus is known to all. The diagnosis of SARS-CoV-2 pneumonia is expected to worsen, and mortality will be higher when combined with myocardial injury (MI). The combination of novel coronavirus infections in patients with MI can cause confusion in diagnosis and assessment, with each condition exacerbating the other, and increasing the complexity and difficulty of treatment. It would be a formidable challenge for clinical practice to deal with this situation. Therefore, this review aims to gather literature on the progress in managing MI related to SARS-CoV-2 pneumonia. This article reviews the definition, pathogenesis, clinical evaluation, management, and treatment plan for MI related to SARS-CoV-2 pneumonia based on the most recent literature, diagnosis, and treatment trial reports. Many studies have shown that early diagnosis and implementation of targeted treatment measures according to the different stages of disease can reduce the mortality rate among patients with MI related to SARS-CoV-2 pneumonia. The reviewed studies show that multiple strategies have been adopted for the management of MI related to COVID-19. Clinicians should closely monitor SARS-CoV-2 pneumonia patients with MI, as their condition can rapidly deteriorate and progress to heart failure, acute myocardial infarction, and/or cardiogenic shock. In addition, appropriate measures need to be implemented in the diagnosis and treatment to provide reasonable care to the patient.https://www.mdpi.com/2308-3425/9/9/307myocardial injurySARS-CoV-2managementpathogenesis
spellingShingle Mohammed Ahmed Akkaif
Ahmad Naoras Bitar
Laith A. I. K. Al-Kaif
Nur Aizati Athirah Daud
Abubakar Sha’aban
Dzul Azri Mohamed Noor
Fatimatuzzahra’ Abd Aziz
Arturo Cesaro
Muhamad Ali SK Abdul Kader
Mohamed Jahangir Abdul Wahab
Chee Sin Khaw
Baharudin Ibrahim
The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia
Journal of Cardiovascular Development and Disease
myocardial injury
SARS-CoV-2
management
pathogenesis
title The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia
title_full The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia
title_fullStr The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia
title_full_unstemmed The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia
title_short The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia
title_sort management of myocardial injury related to sars cov 2 pneumonia
topic myocardial injury
SARS-CoV-2
management
pathogenesis
url https://www.mdpi.com/2308-3425/9/9/307
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