Gallium-68-Labeled KISS1-54 Peptide for Mapping KISS1 Receptor via PET: Initial Evaluation in Human Tumor Cell Lines and in Tumor-Bearing Mice

Gallium-68-Labeled KISS1-54 Peptide for Mapping KISS1 Receptor via PET: Initial Evaluation in Human Tumor Cell Lines and in Tumor-Bearing Mice

Kisspeptins (KPs, KISS1) and their receptor (KISS1R) play a pivotal role as metastasis suppressor for many cancers. Low or lost KP expression is associated with higher tumor grade, increased metastatic potential, and poor prognosis. Therefore, KP expression has prognostic relevance and correlates wi...

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Bibliographic Details
Main Authors: Ina Israel, Gabriele Riehl, Elke Butt, Andreas K. Buck, Samuel Samnick
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceuticals
Subjects:
[<sup>68</sup>Ga]KISS1-54
KISS1-54
KISS1 receptor
GPR54
kisspeptin
human tumor cell lines
Online Access:https://www.mdpi.com/1424-8247/17/1/44

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