Scientific Research Directions on the Histopathology and Immunohistochemistry of the Cutaneous Squamous Cell Carcinoma: A Scientometric Study
<i>Introduction:</i> Cutaneous squamous cell carcinoma (cSCC) is one of the most frequently occurring types of cancer in humans. Scientometric research is an innovative method for analyzing the research trends in various domains, with great implications in the field of medicine. <i>...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-10-01
|
| Series: | Medicina |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1648-9144/58/10/1449 |
| _version_ | 1797471558541770752 |
|---|---|
| author | Iuliu Gabriel Cocuz Maria Elena Cocuz Angela Repanovici Adrian-Horațiu Sabău Raluca Niculescu Andreea-Cătălina Tinca Vlad Vunvulea Corina Eugenia Budin Andreea Raluca Szoke Maria Cătălina Popelea Raluca Moraru Titiana Cornelia Cotoi Ovidiu Simion Cotoi |
| author_facet | Iuliu Gabriel Cocuz Maria Elena Cocuz Angela Repanovici Adrian-Horațiu Sabău Raluca Niculescu Andreea-Cătălina Tinca Vlad Vunvulea Corina Eugenia Budin Andreea Raluca Szoke Maria Cătălina Popelea Raluca Moraru Titiana Cornelia Cotoi Ovidiu Simion Cotoi |
| author_sort | Iuliu Gabriel Cocuz |
| collection | DOAJ |
| description | <i>Introduction:</i> Cutaneous squamous cell carcinoma (cSCC) is one of the most frequently occurring types of cancer in humans. Scientometric research is an innovative method for analyzing the research trends in various domains, with great implications in the field of medicine. <i>Materials and Methods:</i> We searched the Web of Science database with the following established query terms: “Squamous cell carcinoma”, “skin”, and “immunohistochemistry”. After applying the inclusion and exclusion criteria, a total of 76 articles were selected. The present study aims to analyze, based on the frequency of use of keywords with scientometric algorithms and map-based distributions, the trends of the research concerning cSCCs in 2017–2022. <i>Results:</i> A graphical representation based on 11 scientometric maps presented the division of the keywords into seven clusters, from which seven categories of research interest were defined. The clusters represent a multidisciplinary approach to the diagnosis and treatment of cSCCs, cancer diagnostics, patient outcomes, histopathological importance, management of cSCCs, role of progression, and adequate treatment of and importance of immunohistochemistry for cSCCs. The distribution of the citations shows the importance of the available research on cSCCs by analyzing the first five most-cited articles included in our study in direct concordance with the seven defined clusters. <i>Conclusion:</i> The scientometric research method reveals the interest of research in the multidisciplinary approach used to obtain the best outcomes for the patient, including a targeted investigation, as well as diagnostic and treatment options. The trends in the research reveal that histopathological diagnostics and immunohistochemistry, combined with molecular techniques, are the most important tools used to establish a personalized diagnosis, thus increasing the quality of life and life expectancy for patients with cSCCs. |
| first_indexed | 2024-03-09T19:50:53Z |
| format | Article |
| id | doaj.art-134abaefa215450e9a95e2da3f6c9717 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T19:50:53Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-134abaefa215450e9a95e2da3f6c97172023-11-24T01:11:22ZengMDPI AGMedicina1010-660X1648-91442022-10-015810144910.3390/medicina58101449Scientific Research Directions on the Histopathology and Immunohistochemistry of the Cutaneous Squamous Cell Carcinoma: A Scientometric StudyIuliu Gabriel Cocuz0Maria Elena Cocuz1Angela Repanovici2Adrian-Horațiu Sabău3Raluca Niculescu4Andreea-Cătălina Tinca5Vlad Vunvulea6Corina Eugenia Budin7Andreea Raluca Szoke8Maria Cătălina Popelea9Raluca Moraru10Titiana Cornelia Cotoi11Ovidiu Simion Cotoi12Doctoral School of Medicine and Pharmacy, University of Medicine, Pharmacy, Sciences and Technology “George Emil Palade” of Targu Mures, 540142 Targu Mures, RomaniaFundamental Prophylactic and Clinical Disciplines Department, Faculty of Medicine, Transilvania University of Brasov, 500003 Brașov, RomaniaFaculty of Product Design and Environment, Transilvania University of Brasov, 500036 Brasov, RomaniaPathology Department, Mures Clinical County Hospital, 540011 Targu Mures, RomaniaPathology Department, Mures Clinical County Hospital, 540011 Targu Mures, RomaniaPathology Department, Mures Clinical County Hospital, 540011 Targu Mures, RomaniaAnatomy and Embryology Department, University of Medicine, Pharmacy, Sciences and Technology “George Emil Palade” of Targu Mures, 540142 Targu Mures, RomaniaPathophysiology Department, University of Medicine, Pharmacy, Sciences and Technology “George Emil Palade” of Targu Mures, 540142 Targu Mures, RomaniaPathology Department, Mures Clinical County Hospital, 540011 Targu Mures, RomaniaPathology Department, Mures Clinical County Hospital, 540011 Targu Mures, RomaniaAnatomy and Embryology Department, University of Medicine, Pharmacy, Sciences and Technology “George Emil Palade” of Targu Mures, 540142 Targu Mures, RomaniaPharmaceutical Technique Department, University of Medicine, Pharmacy, Sciences and Technology “George Emil Palade” of Targu Mures, 540142 Targu Mures, RomaniaPathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania<i>Introduction:</i> Cutaneous squamous cell carcinoma (cSCC) is one of the most frequently occurring types of cancer in humans. Scientometric research is an innovative method for analyzing the research trends in various domains, with great implications in the field of medicine. <i>Materials and Methods:</i> We searched the Web of Science database with the following established query terms: “Squamous cell carcinoma”, “skin”, and “immunohistochemistry”. After applying the inclusion and exclusion criteria, a total of 76 articles were selected. The present study aims to analyze, based on the frequency of use of keywords with scientometric algorithms and map-based distributions, the trends of the research concerning cSCCs in 2017–2022. <i>Results:</i> A graphical representation based on 11 scientometric maps presented the division of the keywords into seven clusters, from which seven categories of research interest were defined. The clusters represent a multidisciplinary approach to the diagnosis and treatment of cSCCs, cancer diagnostics, patient outcomes, histopathological importance, management of cSCCs, role of progression, and adequate treatment of and importance of immunohistochemistry for cSCCs. The distribution of the citations shows the importance of the available research on cSCCs by analyzing the first five most-cited articles included in our study in direct concordance with the seven defined clusters. <i>Conclusion:</i> The scientometric research method reveals the interest of research in the multidisciplinary approach used to obtain the best outcomes for the patient, including a targeted investigation, as well as diagnostic and treatment options. The trends in the research reveal that histopathological diagnostics and immunohistochemistry, combined with molecular techniques, are the most important tools used to establish a personalized diagnosis, thus increasing the quality of life and life expectancy for patients with cSCCs.https://www.mdpi.com/1648-9144/58/10/1449scientometryhistopathologysquamous cell carcinomaimmunohistochemistrydermatology |
| spellingShingle | Iuliu Gabriel Cocuz Maria Elena Cocuz Angela Repanovici Adrian-Horațiu Sabău Raluca Niculescu Andreea-Cătălina Tinca Vlad Vunvulea Corina Eugenia Budin Andreea Raluca Szoke Maria Cătălina Popelea Raluca Moraru Titiana Cornelia Cotoi Ovidiu Simion Cotoi Scientific Research Directions on the Histopathology and Immunohistochemistry of the Cutaneous Squamous Cell Carcinoma: A Scientometric Study Medicina scientometry histopathology squamous cell carcinoma immunohistochemistry dermatology |
| title | Scientific Research Directions on the Histopathology and Immunohistochemistry of the Cutaneous Squamous Cell Carcinoma: A Scientometric Study |
| title_full | Scientific Research Directions on the Histopathology and Immunohistochemistry of the Cutaneous Squamous Cell Carcinoma: A Scientometric Study |
| title_fullStr | Scientific Research Directions on the Histopathology and Immunohistochemistry of the Cutaneous Squamous Cell Carcinoma: A Scientometric Study |
| title_full_unstemmed | Scientific Research Directions on the Histopathology and Immunohistochemistry of the Cutaneous Squamous Cell Carcinoma: A Scientometric Study |
| title_short | Scientific Research Directions on the Histopathology and Immunohistochemistry of the Cutaneous Squamous Cell Carcinoma: A Scientometric Study |
| title_sort | scientific research directions on the histopathology and immunohistochemistry of the cutaneous squamous cell carcinoma a scientometric study |
| topic | scientometry histopathology squamous cell carcinoma immunohistochemistry dermatology |
| url | https://www.mdpi.com/1648-9144/58/10/1449 |
| work_keys_str_mv | AT iuliugabrielcocuz scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT mariaelenacocuz scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT angelarepanovici scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT adrianhoratiusabau scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT ralucaniculescu scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT andreeacatalinatinca scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT vladvunvulea scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT corinaeugeniabudin scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT andreearalucaszoke scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT mariacatalinapopelea scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT ralucamoraru scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT titianacorneliacotoi scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy AT ovidiusimioncotoi scientificresearchdirectionsonthehistopathologyandimmunohistochemistryofthecutaneoussquamouscellcarcinomaascientometricstudy |