Evolving strategy in treatment of infantile hemangiomas: from steroids to propranolol
Infantile hemangiomas are the most common vascular tumors of the early childhood. Increased incidence of infantile hemangiomas can be attributed to widespread use of assisted reproductive technologies. Majority of hemangiomas in infantile age group resolve spontaneously and only a small proportion o...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Cukurova University
2016-06-01
|
| Series: | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=201781 |
| _version_ | 1797919278496743424 |
|---|---|
| author | Serhan Kupeli |
| author_facet | Serhan Kupeli |
| author_sort | Serhan Kupeli |
| collection | DOAJ |
| description | Infantile hemangiomas are the most common vascular tumors of the early childhood. Increased incidence of infantile hemangiomas can be attributed to widespread use of assisted reproductive technologies. Majority of hemangiomas in infantile age group resolve spontaneously and only a small proportion of the cases with infantile hemangiomas requires treatment. GLUT-ONE acronym (Giant infantile hemangiomas, Liver and/or other visceral organ involvement, Ulcerated or bleeding infantile hemangiomas, Threatening of life, Organ dysfunctioning infantile hemangiomas, Non-localized infantile hemangiomas, Esthetic/cosmetic compromise) can help clinicians for the rapid decision of treatment. Corticosteroids have long been the mainstay treatment for hemangiomatous lesions but after the description of antiproliferative effect of propranolol on severe infantile hemangiomas in 2008, propranolol has been the preferred choice of treatment in many centers. Future studies should be directed to answer the questions regarding the optimal duration of propranolol treatment to overcome recurrences and clinical and histopathological characteristics of infantile hemangiomas that failed treatment with propranolol. [Cukurova Med J 2016; 41(2.000): 354-359] |
| first_indexed | 2024-04-10T13:43:07Z |
| format | Article |
| id | doaj.art-134ecf64d1234e9db00eb37e661a832b |
| institution | Directory Open Access Journal |
| issn | 0250-5150 |
| language | English |
| last_indexed | 2024-04-10T13:43:07Z |
| publishDate | 2016-06-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| spelling | doaj.art-134ecf64d1234e9db00eb37e661a832b2023-02-15T16:11:05ZengCukurova UniversityÇukurova Üniversitesi Tıp Fakültesi Dergisi0250-51502016-06-0141235435910.17826/cutf.201781201781Evolving strategy in treatment of infantile hemangiomas: from steroids to propranololSerhan Kupeli0Cukurova University, Faculty of Medicine Department of Pediatric Oncology and Pediatric Bone Marrow Transplantation Unit, 01330, Balcali, Adana, Turkey.Infantile hemangiomas are the most common vascular tumors of the early childhood. Increased incidence of infantile hemangiomas can be attributed to widespread use of assisted reproductive technologies. Majority of hemangiomas in infantile age group resolve spontaneously and only a small proportion of the cases with infantile hemangiomas requires treatment. GLUT-ONE acronym (Giant infantile hemangiomas, Liver and/or other visceral organ involvement, Ulcerated or bleeding infantile hemangiomas, Threatening of life, Organ dysfunctioning infantile hemangiomas, Non-localized infantile hemangiomas, Esthetic/cosmetic compromise) can help clinicians for the rapid decision of treatment. Corticosteroids have long been the mainstay treatment for hemangiomatous lesions but after the description of antiproliferative effect of propranolol on severe infantile hemangiomas in 2008, propranolol has been the preferred choice of treatment in many centers. Future studies should be directed to answer the questions regarding the optimal duration of propranolol treatment to overcome recurrences and clinical and histopathological characteristics of infantile hemangiomas that failed treatment with propranolol. [Cukurova Med J 2016; 41(2.000): 354-359]http://www.scopemed.org/fulltextpdf.php?mno=201781Infantile hemangiomassteroidspropranololtreatment indicationsglut-one |
| spellingShingle | Serhan Kupeli Evolving strategy in treatment of infantile hemangiomas: from steroids to propranolol Çukurova Üniversitesi Tıp Fakültesi Dergisi Infantile hemangiomas steroids propranolol treatment indications glut-one |
| title | Evolving strategy in treatment of infantile hemangiomas: from steroids to propranolol |
| title_full | Evolving strategy in treatment of infantile hemangiomas: from steroids to propranolol |
| title_fullStr | Evolving strategy in treatment of infantile hemangiomas: from steroids to propranolol |
| title_full_unstemmed | Evolving strategy in treatment of infantile hemangiomas: from steroids to propranolol |
| title_short | Evolving strategy in treatment of infantile hemangiomas: from steroids to propranolol |
| title_sort | evolving strategy in treatment of infantile hemangiomas from steroids to propranolol |
| topic | Infantile hemangiomas steroids propranolol treatment indications glut-one |
| url | http://www.scopemed.org/fulltextpdf.php?mno=201781 |
| work_keys_str_mv | AT serhankupeli evolvingstrategyintreatmentofinfantilehemangiomasfromsteroidstopropranolol |