The need for more holistic immune profiling in next-generation SARS-CoV-2 vaccine trials

The need for more holistic immune profiling in next-generation SARS-CoV-2 vaccine trials

First-generation anit-SARS-CoV-2 vaccines were highly successful. They rapidly met an unforeseen emergency need, saved millions of lives, and simultaneously eased the burden on healthcare systems worldwide. The first-generation vaccines, however, focused too narrowly on antibody-based immunity as th...

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Bibliographic Details
Main Authors: Robert L. Murphy, Eustache Paramithiotis, Scott Sugden, Todd Chermak, Bruce Lambert, Damien Montamat-Sicotte, John Mattison, Steve Steinhubl
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
immune profiling
SARS – CoV – 2
vaccine trial design
vaccines
COVID - 19
cellular immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.923106/full

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