High-Throughput Screen of Natural Product Libraries for Hsp90 Inhibitors
Hsp90 has become the target of intensive investigation, as inhibition of its function has the ability to simultaneously incapacitate proteins that function in pathways that represent the six hallmarks of cancer. While a number of Hsp90 inhibitors have made it into clinical trials, a number of short-...
Main Authors: | Jason Davenport, Maurie Balch, Lakshmi Galam, Antwan Girgis, Jessica Hall, Brian S. J. Blagg, Robert L. Matts |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-02-01
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Series: | Biology |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-7737/3/1/101 |
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