Cytomegalovirus Retinitis in a Patient with Large Cell Diffuse Non-Hodgkin’s Lymphoma

Non-Hodgkin lymphoma is a reticuloendothelial malignancy and usually characterized by malignant proliferation of B cell lymphocytes. Immunosuppressive drugs used in reticuloendothelial malignancy treatments may cause opportunistic infections. Cytomegalovirus (CMV) can also cause such an infection. A...

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Main Author: Ali Kal
Format: Article
Language:English
Published: Clinical and Experimental Ocular Trauma and Infection 2021-08-01
Series:Clinical and Experimental Ocular Trauma and Infection
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/1822671
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author Ali Kal
author_facet Ali Kal
author_sort Ali Kal
collection DOAJ
description Non-Hodgkin lymphoma is a reticuloendothelial malignancy and usually characterized by malignant proliferation of B cell lymphocytes. Immunosuppressive drugs used in reticuloendothelial malignancy treatments may cause opportunistic infections. Cytomegalovirus (CMV) can also cause such an infection. A patient with nonhodgkin lymphoma who had decreased vision due to CMV retinitis is presented. Cytomegalovirus (CMV) retinitis is rarely seen in lymphoma patients and can be confused clinically with intraocular lymphomas. A 27-year-old female patient who received chemotherapy for a non-Hodgkin lymphoma (NHL) presented to our clinic with loss of visual field and decreased vision in both eyes. Fundus examination revealed retinal hemorrhages, exudative deposits and perivascular retinitis in both eyes. As it is thought to have CMV retinitis based on the clinical characteristics of the patient, we also examined serum CMV IgG, IgM and CMV DNA levels to support the diagnosis. Immediately, intravenous ganciclovir treatment was started followed by orally vanganciclovir.
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spelling doaj.art-135770b09b044852a968e71ecc7952852023-02-15T16:09:58ZengClinical and Experimental Ocular Trauma and InfectionClinical and Experimental Ocular Trauma and Infection2667-84622021-08-013224271411Cytomegalovirus Retinitis in a Patient with Large Cell Diffuse Non-Hodgkin’s LymphomaAli Kal0BAŞKENT ÜNİVERSİTESİNon-Hodgkin lymphoma is a reticuloendothelial malignancy and usually characterized by malignant proliferation of B cell lymphocytes. Immunosuppressive drugs used in reticuloendothelial malignancy treatments may cause opportunistic infections. Cytomegalovirus (CMV) can also cause such an infection. A patient with nonhodgkin lymphoma who had decreased vision due to CMV retinitis is presented. Cytomegalovirus (CMV) retinitis is rarely seen in lymphoma patients and can be confused clinically with intraocular lymphomas. A 27-year-old female patient who received chemotherapy for a non-Hodgkin lymphoma (NHL) presented to our clinic with loss of visual field and decreased vision in both eyes. Fundus examination revealed retinal hemorrhages, exudative deposits and perivascular retinitis in both eyes. As it is thought to have CMV retinitis based on the clinical characteristics of the patient, we also examined serum CMV IgG, IgM and CMV DNA levels to support the diagnosis. Immediately, intravenous ganciclovir treatment was started followed by orally vanganciclovir.https://dergipark.org.tr/tr/download/article-file/1822671non-hodgkin lymphoma ; cytomegalovirus retinitisganciclovirvalganciclovir
spellingShingle Ali Kal
Cytomegalovirus Retinitis in a Patient with Large Cell Diffuse Non-Hodgkin’s Lymphoma
Clinical and Experimental Ocular Trauma and Infection
non-hodgkin lymphoma ; cytomegalovirus retinitis
ganciclovir
valganciclovir
title Cytomegalovirus Retinitis in a Patient with Large Cell Diffuse Non-Hodgkin’s Lymphoma
title_full Cytomegalovirus Retinitis in a Patient with Large Cell Diffuse Non-Hodgkin’s Lymphoma
title_fullStr Cytomegalovirus Retinitis in a Patient with Large Cell Diffuse Non-Hodgkin’s Lymphoma
title_full_unstemmed Cytomegalovirus Retinitis in a Patient with Large Cell Diffuse Non-Hodgkin’s Lymphoma
title_short Cytomegalovirus Retinitis in a Patient with Large Cell Diffuse Non-Hodgkin’s Lymphoma
title_sort cytomegalovirus retinitis in a patient with large cell diffuse non hodgkin s lymphoma
topic non-hodgkin lymphoma ; cytomegalovirus retinitis
ganciclovir
valganciclovir
url https://dergipark.org.tr/tr/download/article-file/1822671
work_keys_str_mv AT alikal cytomegalovirusretinitisinapatientwithlargecelldiffusenonhodgkinslymphoma