Salivary Testosterone and Cortisol Levels in Tunisian Elderly Male Patients With Mild Alzheimer’s Disease. Implications of Musical Therapy And/Or Physical Rehabilitation
Changes in salivary testosterone (T) and cortisol (C) levels were assessed in elderly Tunisian male patients with mild Alzheimer’s disease (AD) subjected to music therapy and/or physical rehabilitation. Male patients with mild AD (N = 26; age = 76.23 ± 4.27 years; weight: 74.76 ± 5.36 kg) were rando...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2022.839099/full |
| _version_ | 1828429054649303040 |
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| author | Sarah Chéour Chouaieb Chéour Chiraz Kilani Aymen Guemri Dawser Zineddine Riadh Khélifa Rashmi Supriya Rashmi Supriya Nicola Luigi Bragazzi Nicola Luigi Bragazzi Foued Chéour Julien S. Baker Sabri Gaied-Chortane |
| author_facet | Sarah Chéour Chouaieb Chéour Chiraz Kilani Aymen Guemri Dawser Zineddine Riadh Khélifa Rashmi Supriya Rashmi Supriya Nicola Luigi Bragazzi Nicola Luigi Bragazzi Foued Chéour Julien S. Baker Sabri Gaied-Chortane |
| author_sort | Sarah Chéour |
| collection | DOAJ |
| description | Changes in salivary testosterone (T) and cortisol (C) levels were assessed in elderly Tunisian male patients with mild Alzheimer’s disease (AD) subjected to music therapy and/or physical rehabilitation. Male patients with mild AD (N = 26; age = 76.23 ± 4.27 years; weight: 74.76 ± 5.36 kg) were randomly assigned into four groups for three 60-min sessions per week for 4 months; including Group1 or control group (Co) (n = 6); Group2 (n = 6), participated in physical rehabilitation (PR); Group3 (n = 7), subjected to music therapy (MT) and Group4 (n = 7), participated simultaneously in music therapy and physical rehabilitation (MT + PR). Salivary T levels increased (ηp2 = 0.7) and C levels decreased (ηp2 = 0.69), significantly (p < 0.001) in the PR, MT and MT + PR groups compared to the Co group respectively. Also, increases in salivary T levels and decreases in C levels in MT + PR group were greater compared to the other groups. MT increased T levels (p < 0.001) and decreased C levels (p < 0.05) to a greater extent than the PR group respectively. Changes in salivary T levels were positively (r = 0.83; p < 0.001) and C levels were negatively (r = -0.86; p < 0.001) correlated in the PR, MT and MT + PR groups with changes in MMSE in AD patients. This study highlights that combination of MT and PR holds potential to treat AD. |
| first_indexed | 2024-12-10T17:28:23Z |
| format | Article |
| id | doaj.art-1357f28e7e744aa4b0804689b06f0de0 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-12-10T17:28:23Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-1357f28e7e744aa4b0804689b06f0de02022-12-22T01:39:46ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2022-08-011310.3389/fphys.2022.839099839099Salivary Testosterone and Cortisol Levels in Tunisian Elderly Male Patients With Mild Alzheimer’s Disease. Implications of Musical Therapy And/Or Physical RehabilitationSarah Chéour0Chouaieb Chéour1Chiraz Kilani2Aymen Guemri3Dawser Zineddine4Riadh Khélifa5Rashmi Supriya6Rashmi Supriya7Nicola Luigi Bragazzi8Nicola Luigi Bragazzi9Foued Chéour10Julien S. Baker11Sabri Gaied-Chortane12High Institute of Sport and Physical Education of Ksar Said, Manouba, TunisiaHigh Institute of Sport and Physical Education of Sfax, Sfax, TunisiaHigh Institute of Education and Continuous Training of Tunis, Tunis, TunisiaFaculty of Economics and Management of Sfax, Sfax, TunisiaHigh Institute of Education and Continuous Training of Tunis, Tunis, TunisiaHigh Institute of Sport and Physical Education of Ksar Said, Manouba, TunisiaCentre for Health and Exercise Science Research, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, ChinaLaboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, York University, Toronto, ON, CanadaFaculty of Economics and Management of Sfax, Sfax, TunisiaLaboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, York University, Toronto, ON, CanadaFaculty of Economics and Management of Sfax, Sfax, TunisiaCentre for Health and Exercise Science Research, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, ChinaHigh Institute of Sport and Physical Education of Ksar Said, Manouba, TunisiaChanges in salivary testosterone (T) and cortisol (C) levels were assessed in elderly Tunisian male patients with mild Alzheimer’s disease (AD) subjected to music therapy and/or physical rehabilitation. Male patients with mild AD (N = 26; age = 76.23 ± 4.27 years; weight: 74.76 ± 5.36 kg) were randomly assigned into four groups for three 60-min sessions per week for 4 months; including Group1 or control group (Co) (n = 6); Group2 (n = 6), participated in physical rehabilitation (PR); Group3 (n = 7), subjected to music therapy (MT) and Group4 (n = 7), participated simultaneously in music therapy and physical rehabilitation (MT + PR). Salivary T levels increased (ηp2 = 0.7) and C levels decreased (ηp2 = 0.69), significantly (p < 0.001) in the PR, MT and MT + PR groups compared to the Co group respectively. Also, increases in salivary T levels and decreases in C levels in MT + PR group were greater compared to the other groups. MT increased T levels (p < 0.001) and decreased C levels (p < 0.05) to a greater extent than the PR group respectively. Changes in salivary T levels were positively (r = 0.83; p < 0.001) and C levels were negatively (r = -0.86; p < 0.001) correlated in the PR, MT and MT + PR groups with changes in MMSE in AD patients. This study highlights that combination of MT and PR holds potential to treat AD.https://www.frontiersin.org/articles/10.3389/fphys.2022.839099/fullalzheimer diseaseelderly male patientsmusic therapyphysical rehabilitationtestosteronecortisol |
| spellingShingle | Sarah Chéour Chouaieb Chéour Chiraz Kilani Aymen Guemri Dawser Zineddine Riadh Khélifa Rashmi Supriya Rashmi Supriya Nicola Luigi Bragazzi Nicola Luigi Bragazzi Foued Chéour Julien S. Baker Sabri Gaied-Chortane Salivary Testosterone and Cortisol Levels in Tunisian Elderly Male Patients With Mild Alzheimer’s Disease. Implications of Musical Therapy And/Or Physical Rehabilitation Frontiers in Physiology alzheimer disease elderly male patients music therapy physical rehabilitation testosterone cortisol |
| title | Salivary Testosterone and Cortisol Levels in Tunisian Elderly Male Patients With Mild Alzheimer’s Disease. Implications of Musical Therapy And/Or Physical Rehabilitation |
| title_full | Salivary Testosterone and Cortisol Levels in Tunisian Elderly Male Patients With Mild Alzheimer’s Disease. Implications of Musical Therapy And/Or Physical Rehabilitation |
| title_fullStr | Salivary Testosterone and Cortisol Levels in Tunisian Elderly Male Patients With Mild Alzheimer’s Disease. Implications of Musical Therapy And/Or Physical Rehabilitation |
| title_full_unstemmed | Salivary Testosterone and Cortisol Levels in Tunisian Elderly Male Patients With Mild Alzheimer’s Disease. Implications of Musical Therapy And/Or Physical Rehabilitation |
| title_short | Salivary Testosterone and Cortisol Levels in Tunisian Elderly Male Patients With Mild Alzheimer’s Disease. Implications of Musical Therapy And/Or Physical Rehabilitation |
| title_sort | salivary testosterone and cortisol levels in tunisian elderly male patients with mild alzheimer s disease implications of musical therapy and or physical rehabilitation |
| topic | alzheimer disease elderly male patients music therapy physical rehabilitation testosterone cortisol |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2022.839099/full |
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