Liver Biopsy Hydroxyproline Content Is a Diagnostic for Hepatocellular Carcinoma in Murine Models of Nonalcoholic Steatohepatitis

Liver Biopsy Hydroxyproline Content Is a Diagnostic for Hepatocellular Carcinoma in Murine Models of Nonalcoholic Steatohepatitis

There is increasing evidence that nonalcoholic steatohepatitis (NASH) is a risk factor for hepatocellular carcinoma (HCC) in the absence of cirrhosis, a phenomenon termed noncirrhotic HCC. Early diagnosis of HCC is critical to a favorable prognosis. We tested the hypothesis that hydroxyproline conte...

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Bibliographic Details
Main Authors: Tyler L. Bissoondial, Yiguang Han, Stephanie Mullan, Amrit K. Pabla, Kiera Spahn, Steven Shi, Lana Zheng, Ping Zhou, Kai Jiang, Natalia Prakash, Shraddha Bhutkar, Quaisar Ali, Jingsong Li, Zhijian Hu, Anthony J. Pellicano, Itzhak D. Goldberg, Prakash Narayan
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Diagnostics
Subjects:
NASH
fatty
nonalcoholic
liver
HCC
cancer
Online Access:https://www.mdpi.com/2075-4418/10/10/784

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