Small interfering RNAs based therapies for intracerebral hemorrhage: challenges and progress in drug delivery systems

Small interfering RNAs based therapies for intracerebral hemorrhage: challenges and progress in drug delivery systems

Intracerebral hemorrhage (ICH) is a subtype of stroke associated with higher rates of mortality. Currently, no effective drug treatment is available for ICH. The molecular pathways following ICH are complicated and diverse. Nucleic acid therapeutics such as gene knockdown by small interfering RNAs (...

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Bibliographic Details
Main Authors: Daniyah A Almarghalani, Sai H.S. Boddu, Mohammad Ali, Akhila Kondaka, Devin Ta, Rayyan A Shah, Zahoor A Shah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
intracerebral hemorrhage; lipid-based nanoparticle; nanoparticles; nanotechnology; nonviral vectors; peptide-mediated nanoparticle; polymer-based nanoparticle; sirna therapeutics; sirna-barriers; viral vectors
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=8;spage=1717;epage=1725;aulast=Almarghalani

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